International Journal of Advanced Biological and Biomedical Research

Original Article

1. A study of Mycobacterium tuberculosis Zopf, 1883 (Mycobacteriaceae) in Iraq

Haidar Khalid Mostafa; Mohsen Hashim Risan; Mohammed Al-Faham

Volume 10, Issue 1 , February 2022, Pages 1-17

http://dx.doi.org/10.22034/ijabbr.2021.534391.1362

Abstract

Background: Tuberculosis (TB) is considered to be one of the deadliest bacterial infections in the world and it can have a large impact on global health, drawing international attention ... Read More Background: Tuberculosis (TB) is considered to be one of the deadliest bacterial infections in the world and it can have a large impact on global health, drawing international attention with increasing number of cases worldwide in developed and developing countries. Mycobacterium tuberculosis (MTB) is the main causative agent of TB which is an aerobic pathogenic bacillus that establishes infection in the lungs. It is believed that two billion people are carrying non-eradicated intra-granulomatous Tuberculosis bacilli as LTBI (short for latent tuberculosis infection) and around 10% of those people will be infected with active tuberculosis during their lifetime. Therefore, this study aimed to study Mycobacterium tuberculosis in Iraq.Methods: All bacteriological tests were done in biological safety cabinet class II. Gloves and masks (N 95) were used during the laboratory work. Phenol 5% and ethanol alcohol 70% were used to sterilize and disinfect the benches and hood (IUATLD, 1996). Autoclave was used at 121 °C at 1.5 bar for 20-30 minutes for sterilizing all culture media. The study was conducted at National Reference Lab (NRL) of tuberculosis/Baghdad from July 2016 to December 2016. A total of 188 sputum samples were collected from suspected patient. In addition, 80 samples were collected from healthy subjects Specimens were amassed within the outdoor and as away as feasible from different human beings. Each subject was advised to inhale deeply 2-3 instances, cough out deep from the chest and spit the sputum into sterile prevalent container. We needed to ensure that the specimen was of enough extent (3 to 5 mL) and that it incorporated strong or purulent material. Two samples were gathered from the subject. The first was taken when they reached the institute and the second was taken early morning, earlier than breakfast. The early morning collection represents the pulmonary secretions accrued in a single day, and consequently it typically has a better positivity. Gathered specimens were stored at –20 °C until use.Results: Totally, 118 Tuberculosis suspected samples were used throughout this study; 103 (54.78%) cases were positive using direct assay (AFB smear microscopy) and 85 (45.21%) were negative cases. From the 103 TB patients, 88 (85.43%) represented as new TB cases; the others 15 (14.57%) patients appeared to follow up assessment of the directly observed treatment (DOT) program. The percentage of infected patients was 73 (70.87%) for males to 30 (29.12 %) for females, with over all male to female ratio of 2.43 (73/30) with a highly significant difference (P≤0.01). The age of the study patients ranged from 14 years to 75 years. The mean age was 36 and the median was 30 with highly significant difference between age group. As in many developing countries, direct sputum microscopy is the widely used method for the diagnosis of pulmonary TB in Iraq. Only 103 from 188 patients (suspected) were positive by using ZN smears (Ziehl-Neelsen stain technique). This study for those 188 suspected showed that 119 (63.29%) cases were positive by culture (Lowenstein–Jensen medium) and 69 (36.7%) cases were negative by L.J Culture. This study showed that the percentage of sensitivity, specificity, positive predictive value, and negative predictive value was 74.78%, 79.7%, 86.4% and 64.7%, respectively, using AFB method. The results revealed out of the total 188 specimens, 49 (26.06%) of the specimens were positive by DiaSpot (Tuberculosis Rapid Test on serum) and 139 (73.93%) specimens were negative. This study reported the sensitivity of 33.6% and the specificity of 86.95 % PPV 81.6 and NPV 43.16 for DiaSpot TB Rapid test.Conclusion: Males aged 15 to 45 years are at high risk for TB infection. M. tuberculosis plays a major role for causing tuberculosis in human in Baghdad.

Review Article

2. Role of Immunity Booster Diet, Spices and Herbs, Change Lifestyle: Medical Viewpoints in COVID-19

Saad Alghamdi; Mohammad Asif

Volume 10, Issue 1 , February 2022, Pages 18-31

http://dx.doi.org/10.22034/ijabbr.2021.537187.1365

Abstract

Background: Coronavirus disease 2019 (COVID-19) is a pandemic caused by a novel coronavirus. On 30 January 2020, the first case of the COVID-19 was reported in India and it affects ... Read More Background: Coronavirus disease 2019 (COVID-19) is a pandemic caused by a novel coronavirus. On 30 January 2020, the first case of the COVID-19 was reported in India and it affects the whole world. The impact of various nutrients on the human immune system. To defend itself, the human body has numerous components. The human immune system identifies molecules that are foreign to its structure and responds to them in a useful manner. When a pathogen factor enters the human body, the immune system responds by triggering an immunological response. Methods: Symptoms of COVID-19 may vary from a mild cold to severe respiratory problems and fatality. The symptom may appear in 2 days or as long as 14 days after making contact with the COVID-19 patient. Results: To avoiding contact with an infected person, regular hand washing, wearing a mask may help to prevent and control the COVID-19. There is no specific therapy available for COVID-19. The best way is to prevent infection is to avoid being exposed to the COVID-19. Nutrition is one of the numerous variables that influence immune system function. There is a link between the immune system and nutrition, and malnutrition should not be seen just as a calorie and protein shortage. Conclusions: The body's defensive system should be reinforced to boost immunity, minimize illness risks, and maintain good health. Healthy eating, regular exercise, and an immunological diet, on the other hand, will be a more cost-effective and natural choice.Due to these reasons, the main aim of nourishment is not merely to gain energy andprotein, but to enhance resistance against ailments with some specific nutriment and to turn the inflammatory responsein someone’s best interests. The nutriments which show beneficial effects on the immune system are called immune nutrients and nourishment on these nutriments is called immune diet. The main fields of application of immune diet are patients undergoing surgery, traumatized, cancer, patients who need intensive care, and patients with serious infections.

Original Article

3. Biochemical Characteristics and Antibiotics Susceptibility of Streptococcus Mutans Isolates from Dental Caries in Baghdad City

Aya Raad Salh; Mohsen Hashim Risan; Hameed Majeed Jasim

Volume 10, Issue 1 , February 2022, Pages 32-43

http://dx.doi.org/10.22034/ijabbr.2022.534492.1363

Abstract

Background: Genus Streptococcus comprises important pathogens that have a severe impact on human health. According to the classification in Bergey's Manual of Determinative Bacteriology, ... Read More Background: Genus Streptococcus comprises important pathogens that have a severe impact on human health. According to the classification in Bergey's Manual of Determinative Bacteriology, the genus Streptococcus includes the pyogenic, oral and anaerobic groups of streptococci, as well as a group of other streptococci. S. mutans is a Gram-positive bacterium, which plays a key role in the formation of the dental plaque biofilm as an early coloniser and is the most important bacterium in the formation of dental caries. S. mutans do not have flagella, but do have pili and are non-motile facultative anaerobes that grow optimally at 37 °C. Methods: Eighty samples were collected from patients with different dental caries (pit, fissure and dental roots). The patients had referred to Al-dora Health center and Al-Zewiya Health center in Baghdad city. Bacterial isolates obtained from dental caries samples were streaked on selective medium (Mitis Salivaris Agar) for isolation of S. mutans, then the plates were incubated at 37 °C for 48 hours under anaerobic conditions. Bacterial isolates were identified according to their morphological and cultural characteristics and biochemical tests. The disk diffusion method was used to test the antibiotic susceptibility of the selected isolate to different antibiotics. A sterile cotton swab was dipped in fresh culture of S. mutans and streaked on the surface of Muller-Hinton agar plates by rotating the plate approximately 60 between streaking to ensure even distribution. The inoculated plates were incubated at room temperature for 10 minutes to allow absorption of excess moisture, then antibiotic disks were fixed by sterile forceps on the surface of plates and incubated at 37 °C for 18 hrs.Results: Totally, 98 bacterial isolates were obtained. The results indicated that antibiotic susceptibility pattern of the locally isolated S. mutans S2 was resistant to two antibiotics (bacitracin and erythromycin), while it was sensitive to the other eight antibiotics, consisting amoxicillin, ampicillin, chloramphenicol, vancomycin, clindamycin, imipenem, gentamycin and cephalothin.Conclusion: Locally isolated S. mutans S2 was sensitive to different antibiotics, while it resisted only against bacitracin and erythromycin.

Review Article

4. Review on Iranian Medicinal Plants with anticancer Properties

Ali Salehi Sardoei

Volume 10, Issue 1 , February 2022, Pages 44-56

http://dx.doi.org/10.22034/ijabbr.2021.540129.1368

Abstract

Introduction: Cancer is abnormal and uncontrolled cell proliferation. Carcinogens cause DNA damage and loss of function of tumor suppressor genes, resulting in tumor formation and metastasis. ... Read More

Original Article

5. Evaluation of anti-bacterial (Escherichia coli and Staphylococcus aureus) and anticancer effects of silver nanoparticles synthesized by Melissa officinalis L. extract on several cancer cells (A549, MCF-7, and HeLa)

Faezeh Bashiri Godarzi; Shabnam Shamaei

Volume 10, Issue 1 , February 2022, Pages 57-71

http://dx.doi.org/10.22034/ijabbr.2022.548282.1380

Abstract

ABSTRACT. Silver nanoparticles (AgNPs) with antimicrobial and anticancer properties have been widely used in a variety of fields. This research investigated the antimicrobial effects ... Read More

Original Article

6. Composition of essential oil of Dorema aucheri Boiss. and Allium Jesdianum Boiss. medicinal plants

Yousef Askari

Volume 10, Issue 1 , February 2022, Pages 72-83

http://dx.doi.org/10.22034/ijabbr.2022.545885.1374

Abstract

Background: Medicinal plants contain plant materials such as leaf, root, flower and seed using for producing drugs. Essential oils and extracts of various species of edible and medicinal ... Read More Background: Medicinal plants contain plant materials such as leaf, root, flower and seed using for producing drugs. Essential oils and extracts of various species of edible and medicinal plants, herbs, and spices constitute of very potent natural biologically active agents. Allium jesdianum Boiss and Dorema aucheri Boiss are an important and endangered medicinal plants that main habitats are located in the Zagros Mountains of Iran. Allium jesdianum (Alliaceae family) and Dorema aucheri belongs to Umbelliferae family were collected at summer 2020 from Yasouj in Kohgiluyeh and Boyer-ahmad province during to fruiting stage. The main purpose of this study was to evaluate composition of essential oil of Allium Jesdianum and Dorema aucheri from Kohgiluyeh and Boyer-ahmad province in south west of Iran.Methods: The essential oils of Allium jesdianum and Dorema aucheri were obtained by hydro distillation using a Clevenger type apparatus and in Dorema aucheri was extracted by n-hexane and were analyzed by GC/MS.Results: (E)-Caryophyllene (14.63%), γ-Cadinene (8.58%), Hexadecanoic acid (6.11%), Caryophyllene oxide (5.15%), (E,E)-α-Farnesene (4.05%), Z-Phytol (3.22%), δ-Cadinene (3.18%), Camphor (3.04%) and γ-Eudesmol (2.92%) were the most components of Dorema aucheri, whereas Hexadecanoic acid (18.34%%), Neral (Z-Citral) (13.74%), Dimethyl trisulfide (12.15%), Caryophyllene oxide (8.05%), Gereninal (E-Citral) (5.25%), Borneol (3.31%), Trans-propenyl propyl disulfide (3.17%), Geranyl acetate (2.74%), and β-Caryophyllene (2.65%) were the most constituents in Allium jesdianum oil, respectively.Conclusion: Kohgiluyeh and Boyer-Ahmad has good ethnobotanical potential for medicinal plants. This study is the first contribution to the ethnobotany of this region. We have gathered from this province some considerable knowledge about local medicinal plants such as Allium jesdianum and Dorema aucheri for treating common health problem that is ready to be further investigated in the laboratory.

Original Article

7. Antidiabetic, Antioxidant and Hypolipidemic potentials of Sterculia Setigera Methanol Stem Bark Extract in Alloxan-Induced Diabetic Rats

ABDULKARIM ABBA; Ukwuani-Kwaja Angela Nnenna; JUDE NWAOGU

Volume 10, Issue 1 , February 2022, Pages 84-97

http://dx.doi.org/10.22034/ijabbr.2022.546271.1375

Abstract

Background: Sterculia setigera is one of the medicinal plants used traditionally to treat various diseases with the insertion of diabetes. Diabetes mellitus is a prolonged metabolic ... Read More

1. Diagnosis, Treatment and Prevention of Pregnancy Toxemia in Ewes

Ali Olfati; Gholamali Moghaddam; Mitra Bakhtiari

Volume 1, Issue 11 , November 2013, , Pages 1452-1456

Abstract

Thin ewes or very over-conditioned ewes and ewes carrying multiple pregnanciesare more likely to develop pregnancy toxemia (ketosis). Pregnancy toxemia is a metabolic disorder characterized ... Read More

2. Report of Problems and Difficulties and Solutions to Empower Local Communities of Preservation Plan (a Case Study: Nilang Conventional Territory)

Naser Simani

Volume 1, Issue 6 , June 2013, , Pages 655-659

Abstract

A purpose of Zagros forests preservation plan is to reduce degradation factors through empowering woodman beneficiaries and underdevelopment of rural forested areas which appear as ... Read More

3. Improvement of Morpho-Physiological Traits and Antioxidant Capacity of Zinnia (Zinnia Elegance ‘Dreamland Red’) by Arbuscular Mycorrhizal Fungi (Glomus mosseae) Inoculation

Zahra Heidari; Mohammad Javad Nazari Deljou

Volume 2, Issue 10 , October 2014, , Pages 2627-2631

Abstract

Objective: The inoculation of substrates with arbuscular mycorrhizal fungi (AMF) is one of the most important effective strategies applied and one of the aims of sustainable agriculture. ... Read More

4. Effect of Salicylic Acid on Rooting of Poinsettia (Euphorbia Pulcherrima)

Ali Salehi Sardoei; Sadegh Shahmoradzadeh Fahraji; Hadi Ghasemi

Volume 2, Issue 6 , June 2014, , Pages 1883-1886

Abstract

The poinsettia's species name pulcherrima means "most beautiful" and that it is! Poinsettia's brilliant red floral display held against rich green foliage has made this unlikely species ... Read More

5. Examining the Relationship Between Knowledge Management and Human Resource Performance of Agricultural Cooperatives of East Azarbaijan Province

Mohammad naeim kazempour; Nima kazempour; Ghodrat Adeli; Amir Hossein Askari

Volume 1, Issue 10 , October 2013, , Pages 1253-1262

Abstract

Given the role that knowledge management can play consistently on the changes and the need to develop human resources in the implementation of knowledge management on the one hand and ... Read More

Review Article

1. Iranian Medicinal Plants: From Economically to Ethnomedicine Studies

Ali Salehi Sardoei

Articles in Press, Accepted Manuscript, Available Online from 19 December 2021

http://dx.doi.org/10.22034/ijabbr.2022.540138.1369

Abstract

Introduction: Iran is a privileged country with a high rank in plant biodiversity, including 11 of the 13 globally known climates. According to botanists and researchers, there are ... Read More

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Original Article

2. Monte Carlo Investigation of organs activation in proton and heavy ions cancer therapy by spallation process

Mohammad R Rezaie; Ali R Nooradini; Saeed Mohammadi

Articles in Press, Accepted Manuscript, Available Online from 22 March 2022

http://dx.doi.org/10.22034/ijabbr.2022.549880.1385

Abstract

Background: High-energy heavy ions and protons produced by accelerators are used in industrial and medical applications. Recently, Helium (He), Argon (Ar), Krypton (Kr), Carbon (C) ... Read More

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Review Article

3. Nitrofurans as potent antibacterial agents: a systematic review of literature

Sepideh Rezaei; Sholeh Akbari; Farzad Rahmani; Sara Dabbaghi Varnousfaderani; Saeideh Gomroki; Emad Jafarzadeh

Articles in Press, Accepted Manuscript, Available Online from 08 April 2022

http://dx.doi.org/10.22034/ijabbr.2022.549061.1383

Abstract

Introduction: Bacterial infection and the growing resistance of the bacteria to drugs is a global issue that challenges the health system. Therefore, the development of drugs with a ... Read More

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Original Article

4. MALARIA PREVALENCE AMONG PREGNANT WOMEN IN SOME SELECTED VILLAGES OF YAMALTU-DEBA LOCAL GOVERNMENT AREA, GOMBE STATE NIGERIA.

Ismail Muhammmad; K.S. Muhammad

Articles in Press, Accepted Manuscript, Available Online from 08 April 2022

http://dx.doi.org/10.22034/ijabbr.2022.548976.1382

Abstract

Malaria infection, particularly during pregnancy, is a major public health concern in Nigeria, and there is a scarcity of data on the prevalence and scope of the disease in many areas, ... Read More Malaria infection, particularly during pregnancy, is a major public health concern in Nigeria, and there is a scarcity of data on the prevalence and scope of the disease in many areas, particularly in remote villages that lack basic infrastructure and adequate health facilities for treating and managing the disease. The aim of this study was to investigate the prevalence of malaria infection among pregnant women in some selected villages (Boltongo, Danaji, Kwadon, Liji, and Wajari) of Yamaltu-Deba Local Government Area of Gombe State, Nigeria. The study involved 384 consented pregnant women attending antenatal at Kwadon primary health clinic were enrolled in the study at the Kwadon primary health facility. The subject's venus blood was collected using vein puncture techniques and analyzed microscopically using the Giemsa staining technique. Plasmodium falciparum-malaria was detected on the prepared slide using a microcope with x100 objective lens. Malaria was found in 81 (21.09%) of the 384 blood samples collected, with the highest prevalence documented from Wajari village. Malaria infection was not statistically linked with the respondents' village (x2=5.847, df= 4, P> 0.05). Malaria prevalence in relation to age found that older pregnant women aged 40-45 years old had the greatest prevalence of 2(40.00%), while those aged 36-40years old had the lowest prevalence of 36.0%. Malaria infection was not statistically associated with the subject's age (x2=4.816, df=6, P>0.05). Pregnant women in their first trimester and multigravidae had the greatest prevalence rates of 02(28.57%) and 63(29.57%), respectively. statistically there was no significant link between the pregnant women's trimester (x2=0.355, df=2, P>0.05) and gravidty (x2=1.825, df=2, P>0.05). Yamaltu-Deba L.G.A. recorded a moderate level of malaria infection. A malaria prevention awareness campaign should be carried out in the Local Government, with special attention paid to pregnant women, in order to break the malaria transmission chain and drastically reduce the rate of malaria transmission and infection among pregnant women.

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Original Article

5. Surveillance Studies on Molecular Markers associated with Drug Resistance in DHFR and DHPS genes of Plasmodium falciparum from Gombe L.G.A. Gombe State, Nigeria

Ismail Muhammmad

Articles in Press, Accepted Manuscript, Available Online from 08 April 2022

http://dx.doi.org/10.22034/ijabbr.2022.550156.1386

Abstract

Malaria Chemoprevention depend on synthetic drugs, but the parasite is continuously developing resistance to the antimalarial armament, hence a consequential need for surveillance studies ... Read More

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Volume 10 (2022)

Volume 9 (2021)

Volume 8 (2020)

Volume 7 (2019)

Volume 6 (2018)

Volume 5 (2017)

Volume 4 (2016)

Volume 3 (2015)

Volume 2 (2014)

Volume 1 (2013)

1. A study of Mycobacterium tuberculosis Zopf, 1883 (Mycobacteriaceae) in Iraq

Abstract

2. Role of Immunity Booster Diet, Spices and Herbs, Change Lifestyle: Medical Viewpoints in COVID-19

Abstract

3. Biochemical Characteristics and Antibiotics Susceptibility of Streptococcus Mutans Isolates from Dental Caries in Baghdad City

Abstract

4. Review on Iranian Medicinal Plants with anticancer Properties

Abstract

5. Evaluation of anti-bacterial (Escherichia coli and Staphylococcus aureus) and anticancer effects of silver nanoparticles synthesized by Melissa officinalis L. extract on several cancer cells (A549, MCF-7, and HeLa)

Abstract

6. Composition of essential oil of Dorema aucheri Boiss. and Allium Jesdianum Boiss. medicinal plants

Abstract

7. Antidiabetic, Antioxidant and Hypolipidemic potentials of Sterculia Setigera Methanol Stem Bark Extract in Alloxan-Induced Diabetic Rats

Abstract

1. Diagnosis, Treatment and Prevention of Pregnancy Toxemia in Ewes

Abstract

2. Report of Problems and Difficulties and Solutions to Empower Local Communities of Preservation Plan (a Case Study: Nilang Conventional Territory)

Abstract

3. Improvement of Morpho-Physiological Traits and Antioxidant Capacity of Zinnia (Zinnia Elegance ‘Dreamland Red’) by Arbuscular Mycorrhizal Fungi (Glomus mosseae) Inoculation

Abstract

4. Effect of Salicylic Acid on Rooting of Poinsettia (Euphorbia Pulcherrima)

Abstract

5. Examining the Relationship Between Knowledge Management and Human Resource Performance of Agricultural Cooperatives of East Azarbaijan Province

Abstract

1. Iranian Medicinal Plants: From Economically to Ethnomedicine Studies

Abstract

2. Monte Carlo Investigation of organs activation in proton and heavy ions cancer therapy by spallation process

Abstract

3. Nitrofurans as potent antibacterial agents: a systematic review of literature

Abstract

4. MALARIA PREVALENCE AMONG PREGNANT WOMEN IN SOME SELECTED VILLAGES OF YAMALTU-DEBA LOCAL GOVERNMENT AREA, GOMBE STATE NIGERIA.

Abstract

5. Surveillance Studies on Molecular Markers associated with Drug Resistance in DHFR and DHPS genes of Plasmodium falciparum from Gombe L.G.A. Gombe State, Nigeria

Abstract

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