International Journal of Advanced Biological and Biomedical Research

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1. TCF7L2 Polymorphisms in Type 2 Diabetes, Insight from HRM and ARMS Techniques

hamideh khajeh; Abbas Bahari; Ahmad Rashki

Volume 9, Issue 3 , Summer 2021, Pages 204-214

http://dx.doi.org/10.22034/ijabbr.2021.525681.1351

Abstract

Introduction: Diabetes is a biological problem of life in a new way in human societies, especially in developing countries. Environmental and genetic factors are mutually influential ... Read More

Original Article

2. Psidium Guajava Leaves Ameliorates Mercuric Chloride Induced Neurodegeneration in the Cerebral Cortex of Adult Male Wistar Rats

Joy Ochai; Samuel Sunday Adebisi; Augustine Oseloka Ibegbu

Volume 9, Issue 3 , Summer 2021, Pages 214-227

http://dx.doi.org/10.22034/ijabbr.2021.523093.1348

Abstract

Background: The protective activity exerted by Psidium guajava on the nervous system has been suggested to be via its antioxidant composition; however, its role in mercury-induced neurotoxicity ... Read More

Review Article

3. Antioxidant Properties of Ferulic Acid on cardiovascular diseases

Farzaneh Fazeli

Volume 9, Issue 3 , Summer 2021, Pages 228-240

http://dx.doi.org/10.22034/ijabbr.2021.525197.1350

Abstract

Background: As a dietary phytochemical, Ferulic acid (FA) is caused by metabolism between phenylalanine and tyrosine with physiological functions like anti-inflammatory, anti-diabetic, ... Read More

Original Article

4. Evaluation of Antimicrobial Activity of Rhazya Stricta (Apocynaceae) Extract Prepared with Different Solvents on Staphylococcus Aureus (Staphylococcaceae) Isolated from Humans

Maryam Beigomi; Laleh Shahraki-Mojahed; Batool Heydari-Sadegh; Narjes Dahmardeh; Reza Rouhani; Fereshteh Javadian

Volume 9, Issue 3 , Summer 2021, Pages 241-253

http://dx.doi.org/10.22034/ijabbr.2021.528883.1357

Abstract

Introduction: Bacterial resistance to antibiotics, the first major concern in the 1960s, has reappeared worldwide over the past 20 years. Because these bacteria are not resistant to ... Read More Introduction: Bacterial resistance to antibiotics, the first major concern in the 1960s, has reappeared worldwide over the past 20 years. Because these bacteria are not resistant to various conventional therapies, the medicinal and herbal plants used in different countries should be evaluated for their therapeutic potential. These valuable biological resources are a repository of complex active molecules. Therefore, in this study, we tried to evaluate the antimicrobial activity of some medicinal plant extracts on Staphylococcus aureus isolated from humans.Methods: Rhazya stricta was collected and their species were identified in the botanical laboratory of University of Zabol. To prepare plant extract, 40 g of dried leaves were used in 400 cc of solvent (aqueous, ethanol, methanol, ethyl acetate, and hydro-alcoholic). The various strains of Staphylococcus aureus used in this study were isolated from the human nose and identified by biochemical, bacteriological and growth tests as well as standard tests. Antimicrobial effects were investigated by well diffusion method in Müller Hinton agar medium. Statistix ver10 software was used for statistical calculations. Mean comparison was performed using the LSD at the level of one percent and Excel software was also used to draw the shapes.Results: Rhazya stricta extracts had different inhibitory zone diameters against Staphylococcus aureus at 100 ppm dilution (p <0.01). R. stricta ethanolic extract had the greatest effect (average 8.3 mm) on inhibiting the growth of 6 strains of S. aureus. Then aqueous and hydroalcoholic extracts with an average of 7 mm were in the next ranks. The ethyl acetate extract had the lowest effect on the inhibition of S. aureus. The lowest MIC of R. stricta ethanolic extract against S. aureus samples was 3.1 ppm, which was inhibited by four strains. The lowest MBC was 6.2 ppm.Conclusion: Considering the side effects of chemical drugs and antibiotics as well as the potential effect of ethanolic extract of Rhazya stricta on Staphylococcus aureus, it is recommended to use ethanol solvent to evaluate the antimicrobial activity of R. stricta.

Original Article

5. Investigation of antibacterial and antifungal activities of essential oils of Lippia javanica and Lantana camara (Verbenaceae) harvested in the Haut-Katanga (DR Congo)

Mbayo Kitambala Marsi; Kalonda M Emery; Muhune K Simon; Numbi Wa Ilunga Evodie; Muyumba Nonga Welcome; Lukusa Kabeya Tresor; Misenga T Antoinette; Derek Ndinteh Tantoh; Mbayo Mukala Joseph; Maloba Mwinesenge James; Mulamba Muidikija Jean; Topwe Milongwe Mwene-Mbeja; Lumbu Simbi Jean-Baptiste

Volume 9, Issue 3 , Summer 2021, Pages 254-269

http://dx.doi.org/10.22034/ijabbr.2021.525721.1353

Abstract

Background: Essential oils are volatile compounds characterized by a strong odor, and are generally biosynthesized by aromatic plants as secondary metabolites. This paper aims to extract ... Read More Background: Essential oils are volatile compounds characterized by a strong odor, and are generally biosynthesized by aromatic plants as secondary metabolites. This paper aims to extract the essential oils of Lippia javanica and Lantana camara, and to evaluate their antibacterial, and antifungal activities.Methods: The aerial parts of Lippia javanica and Lantana camara were subjected to hydrodistillation to produce the essential oil. The antimicrobial potential was characterized against six microorganisms, signifying three Gram-negative bacteria (Escherichia coli, Klebsiella pneumoniae and Pseudomonas aeruginosa), two Gram-positive bacteria (Staphylococcus aureus and Streptococcus pneumoniae) and one fungus(Candida albicans) by the disc diffusion method to determine the inhibition zone (in mm) and dilution method to determine the minimal inhibitory concentration (MIC) and the minimum bactericidal concentration (MBC).Results: Essential oil extraction was carried out with an average yield of 0.21% for Lippia javanica, and 0.11% for Lantana camara. The evaluation of the antimicrobial activity showed that Lippia javanica essential oil had a moderate inhibitory activity on Klebsiella pneumoniae, and Streptococcus pneumoniae (MIC: 0.76 mg/mL), on Escherichia coli, Staphylococcus aureus, and Pseudomonas aeruginosa (1.50 mg/mL). The Lantana camara essential oil showed weak inhibitory activity against all strains tested. By diffusion disk method, it was found that Klebsiella pneumoniae was the most sensitive on Lippia javanica essential oil with an inhibition diameter, which evolved from 7 mm to 24 mm; followed by Pseudomonas aeruginosa (21 mm), Escherichia coli (19 mm) and Streptococcus pneumoniae (13 mm) at 15 μL. By means of dilution method, the Lantana camara essential oil showed a low activity against Escherichia coli (MIC: 1.64 mg/mL), Klebsiella pneumonia (MIC: 1.64 mg/mL), Staphylococcus aureus (MIC: 3.28 mg/mL), Pseudomonas aeruginosa (MIC: 3.28 mg/mL), and Candida albicans (MIC: 3.28 mg/mL) but by disc diffusion method, this oil was slightly inhibitory activity on Escherichia coli (10 mm at 15 μL). For the antifungal activity, the Lantana camara essential oil, and Germicide were inactive on Candida albicans when tested by the disk method.Conclusion: The essential oil of Lippia javanica showed moderate antibacterial and antifungal activities, while the essential oil of Lantana camara showed low activity. The activities of essential oils studied were less than that of the gentamicin and more than the activity of Germicide, with two positive controls used.

Original Article

6. Phyto-Mediated silver nanoparticles via melissa officinalis aqueous and methanolic extracts: Synthesis, characterization and biological properties against infectious bacterial strains

Fatemeh Dehghan Nayeri; Sudabeh Mafakheri; Maryam Mirhosseini; R. Z. Sayyed

Volume 9, Issue 3 , Summer 2021, Pages 270-285

http://dx.doi.org/10.22034/ijabbr.2021.525079.1349

Abstract

Background: The present study was aimed to examine the influence of extraction method on the morphology, physico-chemical characteristics and antimicrobial properties of silver nanoparticles ... Read More

Original Article

7. Candida Berkh. (1923) Species and Their Important Secreted Aspartyl Proteinases (SAP) Genes Isolated from Diabetic Patients

Thamer A Muhsen; Mohsen Hashim Risan; Nawras N Alqaysi

Volume 9, Issue 3 , Summer 2021, Pages 286-297

http://dx.doi.org/10.22034/ijabbr.2021.534165.1361

Abstract

Background: Candida Berkh. (1923) occurs naturally in the body. But it becomes opportunistic fungi, meaning that it infects humans when there is any weakening of the immune system, ... Read More Background: Candida Berkh. (1923) occurs naturally in the body. But it becomes opportunistic fungi, meaning that it infects humans when there is any weakening of the immune system, such as exposure to chemotherapy, diabetes, or organ transplantation. Most species of Candida grow at a temperature between 20-40 °C and have a pH of 3-8. Human pathogens of Candida species include C. albicans, C. glabrata, C. lusitaniae, C. parapsilosis, C. tropicalis and C. utili. C. albicans has many virulence factors that facilitate injury process. Virulence factors are considered as a measure of pathogenicity, and it is in the form of fungal toxins, enzymes, or cell structures that facilitate infection, as well as pathogen resistance in different conditions. This study aimed to investigate the frequency of some secreted aspartyl proteinases (SAP) genes from some Candida species isolated from diabetic patientsMethods: Candida spp. were identified on CHROMagar medium by color of each species after incubation at 37 °C for 48 hours such as: C. krusei, C. albicans, C. glabrata, and C. tropicalis. Germ tube formation test was used to distinguish between germ tube-forming species, such as C. albicans and C. dubliniensis , from those that do not produce germ tube. A portion of the isolation was taken and placed in a test tube containing 0.5 ml of serum, and then incubated at 37 °C for 2-4 hours. A drop of serum was taken out and examined under a microscope for the presence of the germ tube. Growth at 45 °C, has the advantage of distinguishing between C. albicans and C. dubliniensis by culturing Candida spp. on SDA medium and, incubation for 48-72 hours at 45 °C.Results: The results of isolation and diagnosis showed that Candida species grew at 37 °C for 48 hours on SDA medium, the shape of the colonies was round or oval-convex, and creamy white, shiny and smooth color. The results of the microscopic examination of the cells were spherical or oval, C. albicans was distinguished by its ability to grow at 45 °C and its ability to form the germ tube. The surface growth test showed the ability of C. tropicalis to grow surface on SDB medium. The medium of CHROMagar showed that C. albicans were light green in color. C. glabrata showed a pale pink color, while C. tropecalis showed a blue color and C. dublineiensis was dark green. DNA extracted samples, including 20 isolates, were used for four species of Candida, 1-9 C. albicans, 10-16 C. glabrata, 17-18 C. dubliniensis and 19-20 C. tropicalis. Parts of the body (mouth, vagina, Urine) detect SAP1 and SAP7 genes by PCR, and after electrophoresis of the PCR product, the results were positive for all Candida species studied as all isolates that contained SAP1 (578bp) and SAP7 (466bp).Conclusion: The SAP genes are among the main virulence factors for the occurrence of candidiasis. SAP1 and SAP7 genes are responsible for digesting and breaking down protein to penetrate the host's tissues.

1. Diagnosis, Treatment and Prevention of Pregnancy Toxemia in Ewes

Ali Olfati; Gholamali Moghaddam; Mitra Bakhtiari

Volume 1, Issue 11 , Autumn 2013, , Pages 1452-1456

Abstract

Thin ewes or very over-conditioned ewes and ewes carrying multiple pregnanciesare more likely to develop pregnancy toxemia (ketosis). Pregnancy toxemia is a metabolic disorder characterized ... Read More

2. Report of Problems and Difficulties and Solutions to Empower Local Communities of Preservation Plan (a Case Study: Nilang Conventional Territory)

Naser Simani

Volume 1, Issue 6 , Spring 2013, , Pages 655-659

Abstract

A purpose of Zagros forests preservation plan is to reduce degradation factors through empowering woodman beneficiaries and underdevelopment of rural forested areas which appear as ... Read More

3. Improvement of Morpho-Physiological Traits and Antioxidant Capacity of Zinnia (Zinnia Elegance ‘Dreamland Red’) by Arbuscular Mycorrhizal Fungi (Glomus mosseae) Inoculation

Zahra Heidari; Mohammad Javad Nazari Deljou

Volume 2, Issue 10 , Autumn 2014, , Pages 2627-2631

Abstract

Objective: The inoculation of substrates with arbuscular mycorrhizal fungi (AMF) is one of the most important effective strategies applied and one of the aims of sustainable agriculture. ... Read More

4. Effect of Salicylic Acid on Rooting of Poinsettia (Euphorbia Pulcherrima)

Ali Salehi Sardoei; Sadegh Shahmoradzadeh Fahraji; Hadi Ghasemi

Volume 2, Issue 6 , Spring 2014, , Pages 1883-1886

Abstract

The poinsettia's species name pulcherrima means "most beautiful" and that it is! Poinsettia's brilliant red floral display held against rich green foliage has made this unlikely species ... Read More

5. GIS-Based Monitoring and Ewss of Desertification (Case Study; Southeastern of Iran)

Gholam Reza Rahdari; Mohammad Reza Rahdari; Ali Akbar Fakhireh; Ali Reza Shahryari; Hassan Khosravi

Volume 1, Issue 10 , Autumn 2013, , Pages 1185-1198

Abstract

Today one of the ecological crisis is the phenomenon of desertification that affecting the world. Desertification is more related to social and anthropogenic issues than natural causes ... Read More

Original Article

1. Bioinformatics Analysis of Bioactive Compounds of Four Capsicum Species against SARS-CoV-2 Infection

Nur Rahmattullah; Estri Laras Arumingtyas; Muhammad Hermawan Widyananda; Alhuda Niftakhul Ahyar; Imam Tabroni

Articles in Press, Accepted Manuscript, Available Online from 05 August 2021

http://dx.doi.org/10.22034/ijabbr.2021.139183.1335

Abstract

Background: Plant-based remedies against Covid-19 and their research to discover antiviral compounds have been growing rapidly. However, there are little interest to explore and collect ... Read More

Original Article

2. Preparation and Study of Physical Properties of Zein Based Composite Films as Food Coatings

Soheil Kianirad; Zahra Beagom Mokhtari-Hosseini; Ashrafalsadat Hatamian-Zaremi; Moein Sarsangi; Sajad Afshar-Yegane; Rasool Setareyi; Ayat Azizi-Alavijeh; Mozhdeh Haddadi

Articles in Press, Accepted Manuscript, Available Online from 09 August 2021

http://dx.doi.org/10.22034/ijabbr.2021.522968.1342

Abstract

Background: Demand for degradable and biocompatible polymers is rapidly increasing, especially in the food packaging sector where it is highly encouraged by environmental management ... Read More

Original Article

3. The Toxicological effect of Cuscuta epithymum and Artemisia absinthium species on CP70 ovarian cancer cells

Homa Hakimian; Saeed Rezaei-Zarchi; Amaneh Javid

Articles in Press, Accepted Manuscript, Available Online from 29 July 2021

http://dx.doi.org/10.22034/ijabbr.2021.526486.1355

Abstract

Background: Ovarian cancer is one of the most common malignancies among women worldwide and is also the fifth leading cause of cancer death among women in recent years. Herbs have been ... Read More

Original Article

4. Screening of bacteria Streptomyces Waksman and Henrici 1943 (Streptomycetaceae) Isolates from Soil Samples in Iraq

Bassam Qasim; Mohsen Hashim Risan

Articles in Press, Accepted Manuscript, Available Online from 17 September 2021

http://dx.doi.org/10.22034/ijabbr.2021.534456.1364

Abstract

Background: The genus Streptomyces Waksman & Henrici 1943 includes aerobic, gram-positive, and filamentous bacteria which produce well developed vegetative hyphae with branches. ... Read More Background: The genus Streptomyces Waksman & Henrici 1943 includes aerobic, gram-positive, and filamentous bacteria which produce well developed vegetative hyphae with branches. The wall consists of a large mixture of different compounds, including peptidoglycan, teichuronic acid, teichoic, and polysaccharides. The peptidoglycan components consist of glycan as a chains of irregular N-acetyl- d-muramic acid (NAM), diaminopimelic acid, and N-acetyl-d-glucosamine (NAG) and DAP, which is unique in the cell walls of prokaryotic microorganisms. The teichoic and teichuronic acid are chemically bonded to peptidoglycan. Methods: One gram of soil samples was used to make suspension, by adding 99 mL of sterile distilled water (stock suspension) into it and shaking it in a shaker at 160 rpm for 30 minutes at room temperature. Serial dilutions from 0.1-0.001 were made from the stock suspension, and left for 10 minutes. After shaking, 0.1 mL of each dilution was cultured on Yeast Extract and Malt Extract agar (YEME) with Streptomycin 50 ug/mL. The inoculated plates were incubated at 28 °C for 7 to 10 days. Based on cultural characteristics, suspected colonies of Streptomyces were selected, which are characterized as small, white, pin-point, rough, chalky, and a clear zone of inhibition around them. These colonies were confirmed their identification by types of Gram’s stain, aerial and substrate mycelium color, pigment production, and pigment color. Streptomyces were re-streaked on International Streptomyces project (ISP) to obtain pure colonies used for identification. Results: The current study aimed to screen bacteria Streptomyces isolates. Only 21 samples of soil were suspected to contain Streptomyces, and 45 isolates were obtained with different morphology types per samples of soil. The colonies suspects were selected basis on color that ranged from gray, white and creamy. The microscopic examination of local Streptomyces spp. after Gram-staining method was conducted. The observations revealed that local Streptomyces is gram positive and rod shaped similar to features of fungal in possessing branched mycelium. The Streptomyces produced extra cellular enzymes like amylase, urease, catalase, protease, Gelatinase, cellulase and phosphatase. Utilization of citrate was positive, with no Melanine reaction production and soluble pigmented, and negative for indole production. Conclusion: The identification of the Streptomyces is a very complex process. Morphological and biochemical characteristics are two important aspects for the classification in the Streptomycetaceae family. By studying the morphological, cultural, and biochemical characteristics, it is observed that the local isolates are belonging to the genus of Streptomyces.

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(Google Scholar) h-index	25
(Google Scholar) i10-index	114
Google Scholar Citation	4133
Web of Science Citation	1145
Average citations per item(WOS)	7.31
h-index in WOS	33
Scopus Citation	1201
H5-median	12
h5-index	9
Issue per year	4
No. of volumes	9
No. of Issues	52
Number of Articles	906
Number of Submissions	367
Rejected Submissions	268
Acceptance rate	26%
Accept Date (Days)	60
Review papers	75
No. of contributors	2,105
Article view	4,130,676
View Per Article	4559.25
PDF download	3,631,158
PDF Download Per Article	4007.9
No. of reviewers	436
Contributing countries	30
No. of databases	37

Volume 9 (2021)

Volume 8 (2020)

Volume 7 (2019)

Volume 6 (2018)

Volume 5 (2017)

Volume 4 (2016)

Volume 3 (2015)

Volume 2 (2014)

Volume 1 (2013)

1. TCF7L2 Polymorphisms in Type 2 Diabetes, Insight from HRM and ARMS Techniques

Abstract

2. Psidium Guajava Leaves Ameliorates Mercuric Chloride Induced Neurodegeneration in the Cerebral Cortex of Adult Male Wistar Rats

Abstract

3. Antioxidant Properties of Ferulic Acid on cardiovascular diseases

Abstract

4. Evaluation of Antimicrobial Activity of Rhazya Stricta (Apocynaceae) Extract Prepared with Different Solvents on Staphylococcus Aureus (Staphylococcaceae) Isolated from Humans

Abstract

5. Investigation of antibacterial and antifungal activities of essential oils of Lippia javanica and Lantana camara (Verbenaceae) harvested in the Haut-Katanga (DR Congo)

Abstract

6. Phyto-Mediated silver nanoparticles via melissa officinalis aqueous and methanolic extracts: Synthesis, characterization and biological properties against infectious bacterial strains

Abstract

7. Candida Berkh. (1923) Species and Their Important Secreted Aspartyl Proteinases (SAP) Genes Isolated from Diabetic Patients

Abstract

1. Diagnosis, Treatment and Prevention of Pregnancy Toxemia in Ewes

Abstract

2. Report of Problems and Difficulties and Solutions to Empower Local Communities of Preservation Plan (a Case Study: Nilang Conventional Territory)

Abstract

3. Improvement of Morpho-Physiological Traits and Antioxidant Capacity of Zinnia (Zinnia Elegance ‘Dreamland Red’) by Arbuscular Mycorrhizal Fungi (Glomus mosseae) Inoculation

Abstract

4. Effect of Salicylic Acid on Rooting of Poinsettia (Euphorbia Pulcherrima)

Abstract

5. GIS-Based Monitoring and Ewss of Desertification (Case Study; Southeastern of Iran)

Abstract

1. Bioinformatics Analysis of Bioactive Compounds of Four Capsicum Species against SARS-CoV-2 Infection

Abstract

2. Preparation and Study of Physical Properties of Zein Based Composite Films as Food Coatings

Abstract

3. The Toxicological effect of Cuscuta epithymum and Artemisia absinthium species on CP70 ovarian cancer cells

Abstract

4. Screening of bacteria Streptomyces Waksman and Henrici 1943 (Streptomycetaceae) Isolates from Soil Samples in Iraq

Abstract

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