Theoretical Evaluation of 5, 6-Diaroylisoindoline-1,3-dione as Potential Carcinogenic Kinase PAK1 Inhibitor: DFT Calculation, Molecular Docking Study and ADMET Prediction
Theoretical Evaluation of 5, 6-Diaroylisoindoline-1,3-dione as Potential Carcinogenic Kinase PAK1 Inhibitor: DFT Calculation, Molecular Docking Study and ADMET Prediction

Mohammad Mazharol Hoque; Ajoy Kumer; Md. Sajib Hussen; Md Wahab Khan

Volume 9, Issue 1 , January 2021, , Pages 77-104

https://doi.org/10.22034/ijabbr.2021.45696

Abstract
  Background: The carcinogenic kinase PAK1 (p21-activated kinase 1) is associated with the progression of many disorders, including Alzheimer's disease, various cancers, type-2 diabetes ...  Read More
The recent development in synthesis and pharmacological evaluation of small molecule to treat Alzheimer's diseases: A review
The recent development in synthesis and pharmacological evaluation of small molecule to treat Alzheimer's diseases: A review

Masome Rahmati

Volume 8, Issue 2 , May and June 2020, , Pages 134-145

https://doi.org/10.33945/SAMI/IJABBR.2020.2.4

Abstract
  Alzheimer's disease is a neurological disorder in which the death of brain cells causes memory loss and cognitive decline. A neurodegenerative type of dementia, the disease starts mild ...  Read More