International Journal of Advanced Biological and Biomedical Research

1. Nitrofurans as potent antibacterial agents: a systematic review of literature

Sepideh Rezaei; Sholeh Akbari; Farzad Rahmani; Sara Dabbaghi Varnousfaderani; Saeideh Gomroki; Emad Jafarzadeh

Articles in Press, Accepted Manuscript, Available Online from 08 April 2022

http://dx.doi.org/10.22034/ijabbr.2022.549061.1383

Abstract

Introduction: Bacterial infection and the growing resistance of the bacteria to drugs is a global issue that challenges the health system. Therefore, the development of drugs with a ... Read More

View Article

2. MALARIA PREVALENCE AMONG PREGNANT WOMEN IN SOME SELECTED VILLAGES OF YAMALTU-DEBA LOCAL GOVERNMENT AREA, GOMBE STATE NIGERIA.

Ismail Muhammmad; K.S. Muhammad

Articles in Press, Accepted Manuscript, Available Online from 08 April 2022

http://dx.doi.org/10.22034/ijabbr.2022.548976.1382

Abstract

Malaria infection, particularly during pregnancy, is a major public health concern in Nigeria, and there is a scarcity of data on the prevalence and scope of the disease in many areas, ... Read More Malaria infection, particularly during pregnancy, is a major public health concern in Nigeria, and there is a scarcity of data on the prevalence and scope of the disease in many areas, particularly in remote villages that lack basic infrastructure and adequate health facilities for treating and managing the disease. The aim of this study was to investigate the prevalence of malaria infection among pregnant women in some selected villages (Boltongo, Danaji, Kwadon, Liji, and Wajari) of Yamaltu-Deba Local Government Area of Gombe State, Nigeria. The study involved 384 consented pregnant women attending antenatal at Kwadon primary health clinic were enrolled in the study at the Kwadon primary health facility. The subject's venus blood was collected using vein puncture techniques and analyzed microscopically using the Giemsa staining technique. Plasmodium falciparum-malaria was detected on the prepared slide using a microcope with x100 objective lens. Malaria was found in 81 (21.09%) of the 384 blood samples collected, with the highest prevalence documented from Wajari village. Malaria infection was not statistically linked with the respondents' village (x2=5.847, df= 4, P> 0.05). Malaria prevalence in relation to age found that older pregnant women aged 40-45 years old had the greatest prevalence of 2(40.00%), while those aged 36-40years old had the lowest prevalence of 36.0%. Malaria infection was not statistically associated with the subject's age (x2=4.816, df=6, P>0.05). Pregnant women in their first trimester and multigravidae had the greatest prevalence rates of 02(28.57%) and 63(29.57%), respectively. statistically there was no significant link between the pregnant women's trimester (x2=0.355, df=2, P>0.05) and gravidty (x2=1.825, df=2, P>0.05). Yamaltu-Deba L.G.A. recorded a moderate level of malaria infection. A malaria prevention awareness campaign should be carried out in the Local Government, with special attention paid to pregnant women, in order to break the malaria transmission chain and drastically reduce the rate of malaria transmission and infection among pregnant women.

View Article

3. Surveillance Studies on Molecular Markers associated with Drug Resistance in DHFR and DHPS genes of Plasmodium falciparum from Gombe L.G.A. Gombe State, Nigeria

Ismail Muhammmad

Articles in Press, Accepted Manuscript, Available Online from 08 April 2022

http://dx.doi.org/10.22034/ijabbr.2022.550156.1386

Abstract

Malaria Chemoprevention depend on synthetic drugs, but the parasite is continuously developing resistance to the antimalarial armament, hence a consequential need for surveillance studies ... Read More

View Article

4. A study of Mycobacterium tuberculosis Zopf, 1883 (Mycobacteriaceae) in Iraq

Haidar Khalid Mostafa; Mohsen Hashim Risan; Mohammed Al-Faham

Volume 10, Issue 1 , February 2022, , Pages 1-17

http://dx.doi.org/10.22034/ijabbr.2021.534391.1362

Abstract

Background: Tuberculosis (TB) is considered to be one of the deadliest bacterial infections in the world and it can have a large impact on global health, drawing international attention ... Read More Background: Tuberculosis (TB) is considered to be one of the deadliest bacterial infections in the world and it can have a large impact on global health, drawing international attention with increasing number of cases worldwide in developed and developing countries. Mycobacterium tuberculosis (MTB) is the main causative agent of TB which is an aerobic pathogenic bacillus that establishes infection in the lungs. It is believed that two billion people are carrying non-eradicated intra-granulomatous Tuberculosis bacilli as LTBI (short for latent tuberculosis infection) and around 10% of those people will be infected with active tuberculosis during their lifetime. Therefore, this study aimed to study Mycobacterium tuberculosis in Iraq.Methods: All bacteriological tests were done in biological safety cabinet class II. Gloves and masks (N 95) were used during the laboratory work. Phenol 5% and ethanol alcohol 70% were used to sterilize and disinfect the benches and hood (IUATLD, 1996). Autoclave was used at 121 °C at 1.5 bar for 20-30 minutes for sterilizing all culture media. The study was conducted at National Reference Lab (NRL) of tuberculosis/Baghdad from July 2016 to December 2016. A total of 188 sputum samples were collected from suspected patient. In addition, 80 samples were collected from healthy subjects Specimens were amassed within the outdoor and as away as feasible from different human beings. Each subject was advised to inhale deeply 2-3 instances, cough out deep from the chest and spit the sputum into sterile prevalent container. We needed to ensure that the specimen was of enough extent (3 to 5 mL) and that it incorporated strong or purulent material. Two samples were gathered from the subject. The first was taken when they reached the institute and the second was taken early morning, earlier than breakfast. The early morning collection represents the pulmonary secretions accrued in a single day, and consequently it typically has a better positivity. Gathered specimens were stored at –20 °C until use.Results: Totally, 118 Tuberculosis suspected samples were used throughout this study; 103 (54.78%) cases were positive using direct assay (AFB smear microscopy) and 85 (45.21%) were negative cases. From the 103 TB patients, 88 (85.43%) represented as new TB cases; the others 15 (14.57%) patients appeared to follow up assessment of the directly observed treatment (DOT) program. The percentage of infected patients was 73 (70.87%) for males to 30 (29.12 %) for females, with over all male to female ratio of 2.43 (73/30) with a highly significant difference (P≤0.01). The age of the study patients ranged from 14 years to 75 years. The mean age was 36 and the median was 30 with highly significant difference between age group. As in many developing countries, direct sputum microscopy is the widely used method for the diagnosis of pulmonary TB in Iraq. Only 103 from 188 patients (suspected) were positive by using ZN smears (Ziehl-Neelsen stain technique). This study for those 188 suspected showed that 119 (63.29%) cases were positive by culture (Lowenstein–Jensen medium) and 69 (36.7%) cases were negative by L.J Culture. This study showed that the percentage of sensitivity, specificity, positive predictive value, and negative predictive value was 74.78%, 79.7%, 86.4% and 64.7%, respectively, using AFB method. The results revealed out of the total 188 specimens, 49 (26.06%) of the specimens were positive by DiaSpot (Tuberculosis Rapid Test on serum) and 139 (73.93%) specimens were negative. This study reported the sensitivity of 33.6% and the specificity of 86.95 % PPV 81.6 and NPV 43.16 for DiaSpot TB Rapid test.Conclusion: Males aged 15 to 45 years are at high risk for TB infection. M. tuberculosis plays a major role for causing tuberculosis in human in Baghdad.

5. Biochemical Characteristics and Antibiotics Susceptibility of Streptococcus Mutans Isolates from Dental Caries in Baghdad City

Aya Raad Salh; Mohsen Hashim Risan; Hameed Majeed Jasim

Volume 10, Issue 1 , February 2022, , Pages 32-43

http://dx.doi.org/10.22034/ijabbr.2022.534492.1363

Abstract

Background: Genus Streptococcus comprises important pathogens that have a severe impact on human health. According to the classification in Bergey's Manual of Determinative Bacteriology, ... Read More Background: Genus Streptococcus comprises important pathogens that have a severe impact on human health. According to the classification in Bergey's Manual of Determinative Bacteriology, the genus Streptococcus includes the pyogenic, oral and anaerobic groups of streptococci, as well as a group of other streptococci. S. mutans is a Gram-positive bacterium, which plays a key role in the formation of the dental plaque biofilm as an early coloniser and is the most important bacterium in the formation of dental caries. S. mutans do not have flagella, but do have pili and are non-motile facultative anaerobes that grow optimally at 37 °C. Methods: Eighty samples were collected from patients with different dental caries (pit, fissure and dental roots). The patients had referred to Al-dora Health center and Al-Zewiya Health center in Baghdad city. Bacterial isolates obtained from dental caries samples were streaked on selective medium (Mitis Salivaris Agar) for isolation of S. mutans, then the plates were incubated at 37 °C for 48 hours under anaerobic conditions. Bacterial isolates were identified according to their morphological and cultural characteristics and biochemical tests. The disk diffusion method was used to test the antibiotic susceptibility of the selected isolate to different antibiotics. A sterile cotton swab was dipped in fresh culture of S. mutans and streaked on the surface of Muller-Hinton agar plates by rotating the plate approximately 60 between streaking to ensure even distribution. The inoculated plates were incubated at room temperature for 10 minutes to allow absorption of excess moisture, then antibiotic disks were fixed by sterile forceps on the surface of plates and incubated at 37 °C for 18 hrs.Results: Totally, 98 bacterial isolates were obtained. The results indicated that antibiotic susceptibility pattern of the locally isolated S. mutans S2 was resistant to two antibiotics (bacitracin and erythromycin), while it was sensitive to the other eight antibiotics, consisting amoxicillin, ampicillin, chloramphenicol, vancomycin, clindamycin, imipenem, gentamycin and cephalothin.Conclusion: Locally isolated S. mutans S2 was sensitive to different antibiotics, while it resisted only against bacitracin and erythromycin.

6. Preparation and Study of Physical Properties of Zein Based Composite Films as Food Coatings

Soheil Kianirad; Zahra Beagom Mokhtari-Hosseini; Ashrafalsadat Hatamian-Zaremi; Moein Sarsangi; Sajad Afshar-Yegane; Rasool Setareyi; Ayat Azizi-Alavijeh; Mozhdeh Haddadi

Volume 9, Issue 4 , December 2021, , Pages 320-330

http://dx.doi.org/10.22034/ijabbr.2021.522968.1342

Abstract

Background: Demand for degradable and biocompatible polymers is rapidly increasing, especially in the food packaging sector where it is highly encouraged by environmental management ... Read More

7. Screening of bacteria Streptomyces Waksman and Henrici 1943 (Streptomycetaceae) Isolates from Soil Samples in Iraq

Bassam Qasim; Mohsen Hashim Risan

Volume 9, Issue 4 , December 2021, , Pages 340-351

http://dx.doi.org/10.22034/ijabbr.2021.534456.1364

Abstract

Background: The genus Streptomyces Waksman & Henrici 1943 includes aerobic, gram-positive, and filamentous bacteria which produce well developed vegetative hyphae with branches. ... Read More Background: The genus Streptomyces Waksman & Henrici 1943 includes aerobic, gram-positive, and filamentous bacteria which produce well developed vegetative hyphae with branches. The wall consists of a large mixture of different compounds, including peptidoglycan, teichuronic acid, teichoic, and polysaccharides. The peptidoglycan components consist of glycan as a chains of irregular N-acetyl- d-muramic acid (NAM), diaminopimelic acid, and N-acetyl-d-glucosamine (NAG) and DAP, which is unique in the cell walls of prokaryotic microorganisms. The teichoic and teichuronic acid are chemically bonded to peptidoglycan.Methods: One gram of soil samples was used to make suspension, by adding 99 mL of sterile distilled water (stock suspension) into it and shaking it in a shaker at 160 rpm for 30 minutes at room temperature. Serial dilutions from 0.1-0.001 were made from the stock suspension, and left for 10 minutes. After shaking, 0.1 mL of each dilution was cultured on Yeast Extract and Malt Extract agar (YEME) with Streptomycin 50 ug/mL. The inoculated plates were incubated at 28 °C for 7 to 10 days. Based on cultural characteristics, suspected colonies of Streptomyces were selected, which are characterized as small, white, pin-point, rough, chalky, and a clear zone of inhibition around them. These colonies were confirmed their identification by types of Gram’s stain, aerial and substrate mycelium color, pigment production, and pigment color. Streptomyces were re-streaked on International Streptomyces project (ISP) to obtain pure colonies used for identification. Results: The current study aimed to screen bacteria Streptomyces isolates. Only 21 samples of soil were suspected to contain Streptomyces, and 45 isolates were obtained with different morphology types per samples of soil. The colonies suspects were selected basis on color that ranged from gray, white and creamy. The microscopic examination of local Streptomyces spp. after Gram-staining method was conducted. The observations revealed that local Streptomyces is gram positive and rod shaped similar to features of fungal in possessing branched mycelium. The Streptomyces produced extra cellular enzymes like amylase, urease, catalase, protease, Gelatinase, cellulase and phosphatase. Utilization of citrate was positive, with no Melanine reaction production and soluble pigmented, and negative for indole production.Conclusion: The identification of the Streptomyces is a very complex process. Morphological and biochemical characteristics are two important aspects for the classification in the Streptomycetaceae family. By studying the morphological, cultural, and biochemical characteristics, it is observed that the local isolates are belonging to the genus of Streptomyces.

8. Evaluation of Relationship between Vitamin D Supplementation Treatment and Hypercalciuria in Patients with Kidney Stones

Elham Javadian; Ali Alidadi; Mahmoud Ali Kaykhaei

Volume 9, Issue 4 , December 2021, , Pages 352-361

http://dx.doi.org/10.22034/ijabbr.2021.537924.1366

Abstract

Background: Vitamin D, especially calcitriol (its active metabolite), increases gastrointestinal calcium absorption. Because urinary calcium excretion is associated with calcium absorption ... Read More

9. Factors Affecting Level of Knowledge on Hepatitis C among Young Couples before Marriage: A Cross-Sectional Study

Aida Moarrefzadeh; Ali Delpisheh; Arash Sarveazad; Jebreil Shamseddin; Mansour Bhardoust

Volume 9, Issue 4 , December 2021, , Pages 362-371

http://dx.doi.org/10.22034/ijabbr.2021.538010.1367

Abstract

Background: Despite the great importance of public knowledge of sexually transmitted diseases such as hepatitis c virus (HCV), very few studies have been conducted in this field in ... Read More Background: Despite the great importance of public knowledge of sexually transmitted diseases such as hepatitis c virus (HCV), very few studies have been conducted in this field in Iran. Therefore, the present study determined the factors affecting the knowledge of young couples before marriage in relation to HCV.Methods: During this cross-sectional study, 1501 couples were assessed, out of which 1110 (73.9%) couples entered the study. A standard questionnaire was used to collect the data. In this questionnaire, first, the demographic characteristics of the participants such as age, gender, level of education, daily extracurricular study, and hours of mass media use were collected, followed by the main items of the study. After data gathering, they were analyzed by IBM SPSS Statistical Software Version 22. Univariate analysis was used to examine the relationship between factors related to the knowledge, and multivariate analysis was used to estimate the related factors.Results: The total score of knowledge about hepatitis C was 0.49 ± 0.29. The total knowledge score for hepatitis C symptoms was 0.27± 0.19. The total score of knowledge about hepatitis C transmission routes was 0.34±0.28. The univariate analysis showed that age, level of education, history of hepatitis in a first degree relative of the family, and social networks were significantly associated with the rate of knowledge about hepatitis C (p <0.05). The multivariate analysis showed that females [(B: 2.11), CI 95% (1.07_3.25), p: 0.014)], higher education level [(B: 4.01), CI 95% (1.98_6 .33), p: 0.014)], history of hepatitis in a first degree relative of the family [(B: 3.56), 95% CI (1.46_5.69), p: 0.011)] and use of social networks [ (B: 2.77), CI 95% (1.11_4.48), p: 0.014)] were significantly associated with the rate of knowledge about HCV.Conclusion: Compared with other studies in this field, the level of knowledge about hepatitis C among young couples in Iran is alarmingly low. In health policies related to hepatitis C, more attention should be paid to the population of men, people with less than a bachelor's degree.

10. TCF7L2 Polymorphisms in Type 2 Diabetes, Insight from HRM and ARMS Techniques

hamideh khajeh; Abbas Bahari; Ahmad Rashki

Volume 9, Issue 3 , September 2021, , Pages 204-214

http://dx.doi.org/10.22034/ijabbr.2021.525681.1351

Abstract

Introduction: Diabetes is a biological problem of life in a new way in human societies, especially in developing countries. Environmental and genetic factors are mutually influential ... Read More

11. Psidium Guajava Leaves Ameliorates Mercuric Chloride Induced Neurodegeneration in the Cerebral Cortex of Adult Male Wistar Rats

Joy Ochai; Samuel Sunday Adebisi; Augustine Oseloka Ibegbu

Volume 9, Issue 3 , September 2021, , Pages 214-227

http://dx.doi.org/10.22034/ijabbr.2021.523093.1348

Abstract

Background: The protective activity exerted by Psidium guajava on the nervous system has been suggested to be via its antioxidant composition; however, its role in mercury-induced neurotoxicity ... Read More

12. Evaluation of Antimicrobial Activity of Rhazya Stricta (Apocynaceae) Extract Prepared with Different Solvents on Staphylococcus Aureus (Staphylococcaceae) Isolated from Humans

Maryam Beigomi; Laleh Shahraki-Mojahed; Batool Heydari-Sadegh; Narjes Dahmardeh; Reza Rouhani; Fereshteh Javadian

Volume 9, Issue 3 , September 2021, , Pages 241-253

http://dx.doi.org/10.22034/ijabbr.2021.528883.1357

Abstract

Introduction: Bacterial resistance to antibiotics, the first major concern in the 1960s, has reappeared worldwide over the past 20 years. Because these bacteria are not resistant to ... Read More Introduction: Bacterial resistance to antibiotics, the first major concern in the 1960s, has reappeared worldwide over the past 20 years. Because these bacteria are not resistant to various conventional therapies, the medicinal and herbal plants used in different countries should be evaluated for their therapeutic potential. These valuable biological resources are a repository of complex active molecules. Therefore, in this study, we tried to evaluate the antimicrobial activity of some medicinal plant extracts on Staphylococcus aureus isolated from humans.Methods: Rhazya stricta was collected and their species were identified in the botanical laboratory of University of Zabol. To prepare plant extract, 40 g of dried leaves were used in 400 cc of solvent (aqueous, ethanol, methanol, ethyl acetate, and hydro-alcoholic). The various strains of Staphylococcus aureus used in this study were isolated from the human nose and identified by biochemical, bacteriological and growth tests as well as standard tests. Antimicrobial effects were investigated by well diffusion method in Müller Hinton agar medium. Statistix ver10 software was used for statistical calculations. Mean comparison was performed using the LSD at the level of one percent and Excel software was also used to draw the shapes.Results: Rhazya stricta extracts had different inhibitory zone diameters against Staphylococcus aureus at 100 ppm dilution (p <0.01). R. stricta ethanolic extract had the greatest effect (average 8.3 mm) on inhibiting the growth of 6 strains of S. aureus. Then aqueous and hydroalcoholic extracts with an average of 7 mm were in the next ranks. The ethyl acetate extract had the lowest effect on the inhibition of S. aureus. The lowest MIC of R. stricta ethanolic extract against S. aureus samples was 3.1 ppm, which was inhibited by four strains. The lowest MBC was 6.2 ppm.Conclusion: Considering the side effects of chemical drugs and antibiotics as well as the potential effect of ethanolic extract of Rhazya stricta on Staphylococcus aureus, it is recommended to use ethanol solvent to evaluate the antimicrobial activity of R. stricta.

13. Candida Berkh. (1923) Species and Their Important Secreted Aspartyl Proteinases (SAP) Genes Isolated from Diabetic Patients

Thamer A Muhsen; Mohsen Hashim Risan; Nawras N Alqaysi

Volume 9, Issue 3 , September 2021, , Pages 286-297

http://dx.doi.org/10.22034/ijabbr.2021.534165.1361

Abstract

Background: Candida Berkh. (1923) occurs naturally in the body. But it becomes opportunistic fungi, meaning that it infects humans when there is any weakening of the immune system, ... Read More Background: Candida Berkh. (1923) occurs naturally in the body. But it becomes opportunistic fungi, meaning that it infects humans when there is any weakening of the immune system, such as exposure to chemotherapy, diabetes, or organ transplantation. Most species of Candida grow at a temperature between 20-40 °C and have a pH of 3-8. Human pathogens of Candida species include C. albicans, C. glabrata, C. lusitaniae, C. parapsilosis, C. tropicalis and C. utili. C. albicans has many virulence factors that facilitate injury process. Virulence factors are considered as a measure of pathogenicity, and it is in the form of fungal toxins, enzymes, or cell structures that facilitate infection, as well as pathogen resistance in different conditions. This study aimed to investigate the frequency of some secreted aspartyl proteinases (SAP) genes from some Candida species isolated from diabetic patientsMethods: Candida spp. were identified on CHROMagar medium by color of each species after incubation at 37 °C for 48 hours such as: C. krusei, C. albicans, C. glabrata, and C. tropicalis. Germ tube formation test was used to distinguish between germ tube-forming species, such as C. albicans and C. dubliniensis , from those that do not produce germ tube. A portion of the isolation was taken and placed in a test tube containing 0.5 ml of serum, and then incubated at 37 °C for 2-4 hours. A drop of serum was taken out and examined under a microscope for the presence of the germ tube. Growth at 45 °C, has the advantage of distinguishing between C. albicans and C. dubliniensis by culturing Candida spp. on SDA medium and, incubation for 48-72 hours at 45 °C.Results: The results of isolation and diagnosis showed that Candida species grew at 37 °C for 48 hours on SDA medium, the shape of the colonies was round or oval-convex, and creamy white, shiny and smooth color. The results of the microscopic examination of the cells were spherical or oval, C. albicans was distinguished by its ability to grow at 45 °C and its ability to form the germ tube. The surface growth test showed the ability of C. tropicalis to grow surface on SDB medium. The medium of CHROMagar showed that C. albicans were light green in color. C. glabrata showed a pale pink color, while C. tropecalis showed a blue color and C. dublineiensis was dark green. DNA extracted samples, including 20 isolates, were used for four species of Candida, 1-9 C. albicans, 10-16 C. glabrata, 17-18 C. dubliniensis and 19-20 C. tropicalis. Parts of the body (mouth, vagina, Urine) detect SAP1 and SAP7 genes by PCR, and after electrophoresis of the PCR product, the results were positive for all Candida species studied as all isolates that contained SAP1 (578bp) and SAP7 (466bp).Conclusion: The SAP genes are among the main virulence factors for the occurrence of candidiasis. SAP1 and SAP7 genes are responsible for digesting and breaking down protein to penetrate the host's tissues.

14. Nanoencapsulation of Phthalate from Melastomastrum Capitatum (Fern.) in Chitosan-Nps as a Target Mediated Drug Delivery for Multi-Drug Resistant Pathogen

Cletus Anes Ukwubile; Emmanuel Oise Ikpefan; Otalu Otalu; Salihu Njidda; Alexander Ezekiel Angyu; Nnamdi D. Menkiti

Volume 9, Issue 2 , June 2021, , Pages 160-180

http://dx.doi.org/10.22034/ijabbr.2021.241725

Abstract

Background: Chitosan nanoparticle (chitosan-NPs) is a polymer obtained from the exoskeletons of crustaceans, and has been applied recently as a carrier for many drug agents. Multi-drug ... Read More

15. The effects of chitosan nanoparticles on genes expression of artemisinin synthase in suspension culture of Artemisia annua L: A comparative study

Bita Ghassemi; Fatemeh Dehghan Nayeri; Ramin Hosseini

Volume 9, Issue 2 , June 2021, , Pages 214-227

http://dx.doi.org/10.22034/ijabbr.2021.523524.1343

Abstract

Background: Despite significant efforts, the artemisinin-based drugs are still very expensive due to the limited production of this metabolite within wild Artemisia spp . plants. Therefore, ... Read More

16. A 3-Dimentional Framework for Studying the Effects of Structural and Physical Properties of the Renal Outer Medulla on Urine Concentrating Mechanism

Maryam Saadatmand; Mohammad Said Saidi; Salman Sohrabi; Mohammad Hossein Banazadeh; Saeed Sadeghi Lafmejani; Hamid Hamed; Bahar Firoozabadi

Volume 9, Issue 1 , March 2021, , Pages 28-47

http://dx.doi.org/10.22034/ijabbr.2021.44618

Abstract

Background: Many theories and mathematical simulations have been proposed concerning urine concentrating mechanism (UCM). Due to significant effect of the tubule and vessel architecture ... Read More

17. An Inexpensive and Simple Method for Isolation Mesenchymal Stem Cell of Human Amnion Membrane

Ali Shadmanesh; Hassan Nazari; Abolfazl Shirazi; Ebrahim Ahmadi; Naser Shams-Esfandabadi

Volume 9, Issue 1 , March 2021, , Pages 119-127

http://dx.doi.org/10.22034/ijabbr.2021.46373

Abstract

Background: Background: Human-amnion membrane mesenchymal stem cells (hAMSCs) are the accessible cells that can be grown in in vitro condition to produce a great number of cells required ... Read More

18. Survey of Plants Used in Folk Medicine in Bali, Gashaka and Sarduana Local Government Areas Taraba State Nigeria for the Treatment of Cancers

Cletus Anes Ukwubile; Jude A. Odugu; Salihu Njidda; Blessing Ogechukwu Umeokoli; Abdulqadir Bukar Bababe; Mathias Simon Bingari; Alexander E. Angyu

Volume 8, Issue 4 , November and December 2020, , Pages 322-339

http://dx.doi.org/10.22034/ijabbr.2020.38756

Abstract

Cancer disease has been on the increase recently in both developed and developing countries of the world resulting in 40 million deaths annually. Ethno-medicinal survey of indigenous ... Read More

19. Regenerative Medicine: Highlight on the Significance of Therapeutics with Novel Strategies

Mozhdeh Haddadi; Mohammad Javad Mousavi

Volume 8, Issue 4 , November and December 2020, , Pages 370-387

http://dx.doi.org/10.22034/ijabbr.2020.39984

Abstract

Background: There is a worldwide effort to present novel approaches for the development of tolerance-induction treatments in regenerative medicine, after years of investigation in clinical ... Read More

20. Reinforcement of a decellularized extracellular matrix-derived hydrogel using nanofibers for cardiac tissue engineering

Shohreh Mashayekhan; Mahboubeh Jahanshahi; Saeed Moghadam

Volume 8, Issue 3 , September and October 2020, , Pages 303-314

http://dx.doi.org/10.33945/SAMI/IJABBR.2020.3.8

Abstract

The role of heart disease in increasing worldwide death and the limited availability of organs for transplantation have encouraged multiple strategies to fabricate functional and implantable ... Read More

21. The evaluation and comparison of thermo-physical, chemical and biological properties of palladium (II) complexes on binuclear diamine ligands with different anions using the DFT method

Mohammad Jahidul Islam; Md. Nuruzzaman Sarker; Ajoy Kumer; Sunanda Paul

Volume 7, Issue 4 , December 2019, , Pages 306-325

http://dx.doi.org/10.33945/SAMI/IJABBR.2019.4.3

Abstract

As cancer is the top killer diseases in the world, the scientists and researchers have been searching the new drugs and remedy methods. Most of the anticancer drugs are organic compounds ... Read More

22. Effect of sub-effective dose of GABA agonists on attenuation of morphine tolerance in rats: Behavioral and electrophysiological studies

Homa Manaheji; Shima Mehrabadi

Volume 7, Issue 4 , December 2019, , Pages 326-334

http://dx.doi.org/10.33945/SAMI/IJABBR.2019.4.4

Abstract

GABAergic drugs can change analgesic effect of morphine. Wide dynamic range (WDR) neurons play an important role in pain transmission and may change behaviors in morphine tolerance. ... Read More

23. Bioorganic investigation of encapsulated Cysteine derivative into polymeric nanocarrier

Ehab M. Ali; Ahmed Hamed

Volume 7, Issue 4 , December 2019, , Pages 342-352

http://dx.doi.org/10.33945/SAMI/IJABBR.2019.4.6

Abstract

In this work, the copolymer-based synthesized Cysteine-loaded nanocarriers prepared by a routine protocol, coprecipitation method. It is the first report to investigate the neuroprotective ... Read More

24. The Therapeutic Effect of Statins on Survival of Patients with Gastrointestinal Cancer: a Review

Ali Olfati; Nasrollah Moradi-kor

Volume 7, Issue 3 , September 2019, , Pages 191-203

http://dx.doi.org/10.33945/SAMI/IJABBR.2019.3.1

Abstract

Cancer -can significantly have ruining effects on very high of human beings, social, and economic condition. Gastrointestinal (GI) cancer has been reported as one of the most prevalent ... Read More

25. Pretreatment Of Nano Chitosan And Nano Calcium (X. gideon) In The Application Of Acetic Acid To Enamel Hardness

Ade Komariah Komariah; Selly Parcelia; Bambang S. Trenggono

Volume 7, Issue 3 , September 2019, , Pages 246-254

http://dx.doi.org/10.33945/SAMI/IJABBR.2019.3.6

Abstract

Background:Chitosan and Calcium are one of the natural polymeric materials obtained from the exoskeleton of Xylotrupes gideon through demineralization, deproteinization and deacetylation ... Read More

Articles in Press

Current Issue

Volume 10 (2022)

Volume 9 (2021)

Volume 8 (2020)

Volume 7 (2019)

Volume 6 (2018)

Volume 5 (2017)

Volume 4 (2016)

Volume 3 (2015)

Volume 2 (2014)

Volume 1 (2013)

Main Subjects = Biomedical Sciences Number of Articles: 72

1. Nitrofurans as potent antibacterial agents: a systematic review of literature

Abstract

2. MALARIA PREVALENCE AMONG PREGNANT WOMEN IN SOME SELECTED VILLAGES OF YAMALTU-DEBA LOCAL GOVERNMENT AREA, GOMBE STATE NIGERIA.

Abstract

3. Surveillance Studies on Molecular Markers associated with Drug Resistance in DHFR and DHPS genes of Plasmodium falciparum from Gombe L.G.A. Gombe State, Nigeria

Abstract

4. A study of Mycobacterium tuberculosis Zopf, 1883 (Mycobacteriaceae) in Iraq

Abstract

5. Biochemical Characteristics and Antibiotics Susceptibility of Streptococcus Mutans Isolates from Dental Caries in Baghdad City

Abstract

6. Preparation and Study of Physical Properties of Zein Based Composite Films as Food Coatings

Abstract

7. Screening of bacteria Streptomyces Waksman and Henrici 1943 (Streptomycetaceae) Isolates from Soil Samples in Iraq

Abstract

8. Evaluation of Relationship between Vitamin D Supplementation Treatment and Hypercalciuria in Patients with Kidney Stones

Abstract

9. Factors Affecting Level of Knowledge on Hepatitis C among Young Couples before Marriage: A Cross-Sectional Study

Abstract

10. TCF7L2 Polymorphisms in Type 2 Diabetes, Insight from HRM and ARMS Techniques

Abstract

11. Psidium Guajava Leaves Ameliorates Mercuric Chloride Induced Neurodegeneration in the Cerebral Cortex of Adult Male Wistar Rats

Abstract

12. Evaluation of Antimicrobial Activity of Rhazya Stricta (Apocynaceae) Extract Prepared with Different Solvents on Staphylococcus Aureus (Staphylococcaceae) Isolated from Humans

Abstract

13. Candida Berkh. (1923) Species and Their Important Secreted Aspartyl Proteinases (SAP) Genes Isolated from Diabetic Patients

Abstract

14. Nanoencapsulation of Phthalate from Melastomastrum Capitatum (Fern.) in Chitosan-Nps as a Target Mediated Drug Delivery for Multi-Drug Resistant Pathogen

Abstract

15. The effects of chitosan nanoparticles on genes expression of artemisinin synthase in suspension culture of Artemisia annua L: A comparative study

Abstract

16. A 3-Dimentional Framework for Studying the Effects of Structural and Physical Properties of the Renal Outer Medulla on Urine Concentrating Mechanism

Abstract

17. An Inexpensive and Simple Method for Isolation Mesenchymal Stem Cell of Human Amnion Membrane

Abstract

18. Survey of Plants Used in Folk Medicine in Bali, Gashaka and Sarduana Local Government Areas Taraba State Nigeria for the Treatment of Cancers

Abstract

19. Regenerative Medicine: Highlight on the Significance of Therapeutics with Novel Strategies

Abstract

20. Reinforcement of a decellularized extracellular matrix-derived hydrogel using nanofibers for cardiac tissue engineering

Abstract

21. The evaluation and comparison of thermo-physical, chemical and biological properties of palladium (II) complexes on binuclear diamine ligands with different anions using the DFT method

Abstract

22. Effect of sub-effective dose of GABA agonists on attenuation of morphine tolerance in rats: Behavioral and electrophysiological studies

Abstract

23. Bioorganic investigation of encapsulated Cysteine derivative into polymeric nanocarrier

Abstract

24. The Therapeutic Effect of Statins on Survival of Patients with Gastrointestinal Cancer: a Review

Abstract

25. Pretreatment Of Nano Chitosan And Nano Calcium (X. gideon) In The Application Of Acetic Acid To Enamel Hardness

Abstract

Main Subjects = Biomedical Sciences
Number of Articles: 72