TY - JOUR ID - 7871 TI - Effect of Hydro-Methanolic Extract of Xylopia Aethiopica on Sexual Behaviour in Male Wister Rats JO - International Journal of Advanced Biological and Biomedical Research JA - IJABBR LA - en SN - 2383-2762 AU - M. Adienbo, Ologhaguo AU - Nwafor, Arthur AU - S. Ogbomade, Ronami AD - Department of Human Physiology, Faculty of Basic Medical Sciences, College of Health Sciences, University of Port Harcourt, Port Harcourt Nigeria Y1 - 2013 PY - 2013 VL - 1 IS - 9 SP - 1078 EP - 1085 KW - Xylopia aethiopice KW - Sexual behavior KW - Aphrodisiac KW - Male sexual disorder DO - N2 - This study aims to investigate the effect of xylopia aethiopica on the sexual behavior of adult male rats. Fort eight adult male wistar rats were used for the study. They were randomly divided into four groups of 6 animals each: group 1 was control, while groups 2, 3 and 4 were test groups treated daily with 0.5, 2 and 10 mg/kg body weight respectively of hydro-methanolic fruit extract of xylopia aethiopice for 30 consecutive days followed by 30 days recovery. Mating test was performed on six animals from each group on days 30 and 60 of the study. Also, 6 animals were sacrificed from each group and blood collected for serum testosterone assay on 31st and 61st days of the study. Results show significant (P<0.05) dose dependent increase in ejaculation latency (EL), and post ejaculatory interval (PEI) with significant decrease (P<0.05) in ejaculation frequency (EF) and in serum testosterone levels in rats in all the test groups. We conclude that xylopia aethiopice enhances copulatory performance without altering sexual excitement, arousal and motivation; therefore could be useful in the management of male sexual dysfunction UR - https://www.ijabbr.com/article_7871.html L1 - https://www.ijabbr.com/article_7871_2d3c9235c0d147a5c9b11e7e39273a2d.pdf ER -