1Department of Agronomy, Faculty of Agriculture, University of Zabol, Zabol, Iran
2Zabol University of Medical Sciences, Zabol, Iran
3Department of Plant Breeding and Biotechnology, University of Zabol, Zabol, Iran
4Zabol Medicinal Plant Research Center, Zabol University of Medical Sciences, Zabol, Iran
Objective: Teucrium polium L. (family Lamiaceae) is a wild-growing flowering plant, found abundantly in South-Western Asia, Europe and North Africa. Traditionally, T. polium has been used for different pathological conditions such as gastrointestinal disorders, inflammations, diabetes and rheumatism. The purpose of this study was to evaluate the antimicrobial effect of ethanol extract of Teucrium polium against Salmonella typhimurium isolates from poultry is resistant to penicillin. Methods: Teucrium polium extract using vacuum from the center (Rotary) were 12 strains of Salmonella typhimurium was isolated from poultry in the city of Zabol. Minimum inhibitory concentrations of MBC Teucrium polium extract in different concentrations by dilution in the wells was determined on bacteria. Susceptibility to several antibiotics by Kirby-Bauer disk diffusion standard were evaluated. Results: The result of herbal extraction showed the most MIC (the minimum inhibitory concentration) was 10mg/ml concentration that 2 strains of them were inhibited by this concentration Teucrium polium. The lowest MIC was 2/5 ppm concentration that two strain of Salmonella were inhibited. Although the clinical relevance of extracts and essential oils because of fewer side effects than other current treatments for common antibiotics, it seems valuable, but more research to clinical application of the mechanism of action of ethanol extract and purified effective composition of this plant is on microbial agents.