Document Type: Short communication


1 Department of Agronomy, Faculty of Agriculture, University of Zabol, Zabol, Iran

2 Zabol University of Medical Sciences, Zabol, Iran

3 Department of Plant Breeding and Biotechnology, University of Zabol, Zabol, Iran

4 Zabol Medicinal Plant Research Center, Zabol University of Medical Sciences, Zabol, Iran


Objective: Teucrium polium L. (family Lamiaceae) is a wild-growing flowering plant, found abundantly in South-Western Asia, Europe and North Africa. Traditionally, T. polium has been used for different pathological conditions such as gastrointestinal disorders, inflammations, diabetes and rheumatism. The purpose of this study was to evaluate the antimicrobial effect of ethanol extract of Teucrium polium  against Salmonella typhimurium isolates from poultry is resistant to penicillin. Methods: Teucrium polium extract using vacuum from the center (Rotary) were 12 strains of Salmonella typhimurium was isolated from poultry in the city of Zabol. Minimum inhibitory concentrations of MBC Teucrium polium extract in different concentrations by dilution in the wells was determined on bacteria. Susceptibility to several antibiotics by Kirby-Bauer disk diffusion standard were evaluated. Results: The result of herbal extraction showed the most MIC (the minimum  inhibitory concentration) was 10mg/ml concentration that 2 strains of them were inhibited by this concentration Teucrium polium. The lowest MIC was 2/5 ppm concentration that two strain of Salmonella were inhibited. Although the clinical relevance of extracts and essential oils because of fewer side effects than other current treatments for common antibiotics, it seems valuable, but more research to clinical application of the mechanism of action of ethanol extract and purified effective composition of this plant is on microbial agents.


Main Subjects

Farnsworth NR .1989. Screening plants for new medicines. In: Wilson EO, editor. Biodiversity, Part II. Washington: National Academy Press, 83ñ97.
Belmekki N, Bendimerad N, Bekhechi C and Fernandez X. 2013. Chemical analysis and antimicrobial activity of Teucrium polium L. essential oil from Western Algeria. Journal of Medicinal Plants Research. 7(14), pp. 897-902.
Bajpai M, Pande A, Tewari SK and Prakash D, 2005. Phenolic contents and
antioxidant activity of some food and medicinal plants. Inter. J. Food Sci Nutr., 56(4): 287-291.
Coste H. 1909. Flore descriptive et illustrÈe de la France, de la Corse et des contrÈes limitrophes. Librairie Blanchard: Paris, 139ñ140.
Bonnier G. 1990. La grande flore en couleur. Librairie Belin: Paris, 943ñ948.
Chang FR, Hwang TL, Yang YL, Li CL, Wu CC, Issa HH, Hsieh WB and Wu YC. 2006. Anti-Inflammatory and Cytotoxic diterpenes from formosan Polyalthia longifolia var. pendula. Planta Med., 72: 1344-1347.
Acar JF and Goldstein FW.1996. Disc Susceptibility Test. In: Lo-Rian, V. (Ed.), Antibiotics in Laboratory Medicine. 4th Edn., Williams & Wilkins, Baltimore, London, 1-52.
Ali Shtayeh MS, Yaniv Z, Mahajna J. 2000. Ethnobotanical survey in the Palestinian area: A classification of the healing potential of medicinal plants. Journal of Ethnopharmacology 73:221-232
Abdollahi M, Karimpour H, Monsef-Esfehani HR .2003. Antinociceptive effects of Teucrium polium L. total extract and essential oil in mouse writhing test. Pharm. Res. 48:31-35.
Couladis M, Tzakou O, Verykokidou E, Harvala C .2003. Screening of some Greek aromatic plants for antioxidant activity. Phytotherapy Res. 17:194-195.
Rasekh HR, Khoshnood-Mansourkhani MJ, Kamalinejad
M .2001. Hypolipidemic effects of Teucrium polium in rats. Fitoterapia 72:937- 939.
Gharaibeh MN, Elayan HH, Salhab AS .1988. Hypoglycemic effects of Teucrium polium. J. Ethnopharm. 24:93-99.
Shakibaiee M, Hydari M, Ahmadinezhad M and Mohammadi M. 2000. [Plasmid curing activity of five plant extracts on multiple resistant plasmid bearing
Klebsiella pnumoniae strains] Persian. J Guilan Univ Med Sci .9(33): 1-10
Sarac N, Ugur A.2007. Antimicrobial activities and usage in folkloric medicine of some Lamiaceae species growing in Mugla, Turkey. EurAsia J Bio Sci . 4: 28-37.
Zerroug MM, Zouaghi M, Biumerfeg S, Baghiani A, Nicklin J and Arrar L.2011. Antibacterial Activity of Extracts of Ajuga Iva, and Teucrium Polium Advances in Environmental Biology, 5(2): 491-495.
Darabpour E, Motamedi H and Seyyed Nejad SM 2010. Antimicrobial properties of Teucrium polium against some clinical pathogens. Asian Paci. J. Tropic. Med.
Purnavab S, Ketabchi S, Rowshan V.2015. Chemical composition and antibacterial activity of methanolic extract and essential oil of Iranian Teucrium polium against some of phytobacteria. Nat Prod Res. 13:1-4.
Elmasri WA, Hegazy ME, Aziz M, Koksal E, Amor W, Mechref Y, Hamood AN, Cordes DB, ParÈ PW. 2014. Biofilm blocking sesquiterpenes from Teucrium
polium.Phytochemistry. 103:107-13. doi:10.1016/j.phytochem.2014.03.029.
Autore G, Capasso F, De Fusco R, Fasulo MP, Lembo M, Mascolo N, Menghini A. 1984. Antipyretic and antibacterial actions of Teucrium polium (L.). Pharmacol
Res Commun.16(1):21-9.