Hypercholesterolemia Ameliorating Effect of Bangladeshi High Yield Variety Rice Bran Oil

Rahman, Mohammad Azizur; Ferdous, Jannatul; Hosen, Shakir; Hasan, Mahmudul; Parvin, Afroza; Shojib, Habibul Bari

doi:10.22034/ijabbr.2021.44619

Document Type : Original Article

Authors

¹ Department of Biochemistry and Molecular Biology, Jahangirnagar University, Savar, Dhaka 1342, Bangladesh

² Grain Quality and Nutrition (GQN) Division, Bangladesh Rice Research Institute (BRRI), Gazipur, Bangladesh

https://doi.org/10.22034/ijabbr.2021.44619

Abstract

Background: Hypercholesterolemia led cardiovascular disease (CVD) complications are plaguing the globe. In the present study,Bangladesh Rice Research Institute (BRRI) high yield variety (HYV) rice named as BR5 was selected for extracting bran oil followed by fatty acid analysis and in vivo hypocholesterolemic effect of the extracted rice bran oil (RBO) for the sake of ameliorating CVD.
Method: RBO was extracted using n-Hexane followed by fatty acid analysis and anti-hypocholesterolemic study on rats against soybean oil (SBO), mustard oil (MBO) and butter oil (BTO) followed by organ function tests. Study period was four weeks. Then the rats were killed, their blood was collected and serum biochemical parameters were analyzed using semi-auto analyzer.
Results: Fattyacid analyses revealed BR5 was the best among the six HYVs of rice. Compared with the other edible oils, RBO derived from BR5 showed significantly increasing effect upon plasma total cholesterol and low density lipoprotein cholesterol lowering while high density lipoprotein cholesterol increasing. Toxicological studies showed no detrimental effect of BR5 derived RBO on cardiac, renal and hepatic functions.
Conclusion: BR5 is a rich source of RBO that provides balanced fatty acid support and exerts hypocholesterolemic effects without any detectable side effects. Consumption of BR5 derived RBO would aid in CVD amelioration.

Graphical Abstract

Keywords

Main Subjects

Biochemistry

References

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International Journal of Advanced Biological and Biomedical Research

Hypercholesterolemia Ameliorating Effect of Bangladeshi High Yield Variety Rice Bran Oil

References

References

Volume 9, Issue 1 - Serial Number 1
January 2021
Pages 48-57

Hypercholesterolemia Ameliorating Effect of Bangladeshi High Yield Variety Rice Bran Oil

References

References

Volume 9, Issue 1 - Serial Number 1January 2021Pages 48-57

Volume 9, Issue 1 - Serial Number 1
January 2021
Pages 48-57