Cholecystitis presents as acute or chronic. Severity of cholecystitis depends on several factors. Aim of this study was to evaluate severity of laparoscopic cholecystectomy findings based on gender type. In a retrospective and epidemiological study, a total of 101 patients who were underwent laparoscopic cholecystectomy were selected from 2001 to 2006 in university affiliated hospitals of Ahwaz, Iran. Among 101 patients were assessed in our study, 41(40.6%) were men and 60(59.4%) were women. Evaluating of patients according to sex revealed that proportion of empyema, gallbladder stones, gangrene, switch to open cholecystectomy, and acute cholecystitis were different statistically and were higher in men than women. But chronic cholecystitis was significantly lower in men than women. As our findings demonstrated, we suggest that men with cholecystitis need rapid surgical intervention to prevent and reduce complications of disease.