Document Type : Review Article
1 Department of Pharmacology, Iranian Society of Physiology and Pharmacology, Tehran, Iran
2 MD Graduated, Guillan University of Medical Science, Guillan, Iran
3 M.sc. Student of Food Industrial, Sarvestan Branch, Islamic Azad University, Sarvestan, Iran
Fenugreek is an medicinal plant that use in disease some therapy. This plant use for blood lipids and sugar decreasing in diabetic and non diabetic peoples and have antioxidant and antibacterial activity. The plant contains active constituents such as alkaloids, flavonoids, steroids, Saponins etc. It is an old medicinal plant. It has been commonly used as a traditional food and medicine. Fenugreek is known to have hypoglycemic, and hypocholesterolaemic, effects, Anti-inflammatory effects. Recent research has identified fenugreek as a valuable medicinal plant with potential for curing diseases and also as a source for preparing raw materials of pharmaceutical industry, like in steroidal hormones. Since fenugreek is a self-pollinated crop, a mutation breeding method can be used to generate mutants with a determinate growth habit. Irradiation and chemical mutagens can be used to produce point mutations in fenugreek
Ahmed MA., Ibrahim OM., Elham AB., 2010. Effect of bio and mineral phosphorus fertilizer on the growth, productivity and nutritional value of fenugreek (Trigonella foenum graecum L.) in Newly Cultivated Land. Res. J. Agriculture and Biological Sci, 6 (3): 339 – 48.
Analava M., Debaprasad B., 2004. Dose-dependent effects of fenugreek composite in diabetes with dislipidaemia. Internet J Food Safety, 8, 49-55.
Basu SK., 2006. Seed production technology for fenugreek (Trigonella foenum-graecum L.) in the Canadian. Master of Science Thesis. Department of Biological Sciences University of Lethbridge, Alberta, Canada. p: 202.
Basu SK., Acharya SN., Bandara MS., Friebel D.,Thomas JE., 2009. Effects of genotype and environment on seed and forage yield in fenugreek (Trigonella foenum-graecum L.) grown in western Canada. Australian J. Crop Sci. Southern Cross Journals, 3(6): 305–14.
Basu SK., Acharya SN., Thomas JE., 2008. Appilcation of phosphate fertilizer and harvest management for important fenugreek (Trigonella foenum-graecum L.) seed and forage yield in a dark brown soil zone
of Canada. KMITL Sci Tech J, 8 (1): 1 –7.
Dawidar AM., Fayez MBE., 1972. Thin-layer chromatographic detection and estimation of steroid sapogenins. Z. Anal. Chem, 259: 283 –285.
Duke AJ., 1986. Handbook of Legumes of World Economic Importance, Plemus Press, New York and London. pp: 345.
Elujoba AA., Hardman R., 1985. Fermentation of powdered fenugreek seeds for increased sapogenin yields. Fitoterapia, 56 (6): 368 –70.
Ethan B., Grace K., Michael S., 2003. Therapeutic Applications of Fenugreek. Altern Med Rev, 8(1):20-27.
Fazli FRY., and Hardman R., 1968. The spice, fenugreek (Trigonella foenum-graecum L.): Its conmmercial varieties of seed as a source of diosgenin. Tro. Sci., 10: 66-78.
Hajimehdipoor H., Sadat-Ebrahimi SE., Amanzadeh Y., Izaddoost M., Givi E., 2010. Identification and Quantitative Determination of 4-Hydroxyisoleucine in Trigonella foenumgraecum L. from Iran. J. Medicinal Plants, 9 (6): 29 – 34.
Hardman R, and Fazli FRY. 1972. Methods of screening the genus Trigonella for steroidal sapogenins. Planta Medica, 21: 131–138.
Home remedies guide. Fenugreek medicinal properties and benefits. Available from: http://www.homeremedies-guide.com/herbs/fenugreek.htm.
Indian food. Fenugreek. Available from: http://www.indianetzone.com/1/fenugreek.htm.
Jain V., Jain P., Sharma S., Kakani R., 1995. Hypolipidaemic activity of syndrex, a hydroalcoholic extract of fenugreek seeds Single blind clinical study. Int Med J, 89:1-41.
Khanna P., Jain SC., 1973. Diosgenin, gitogenin and tigogenin from Trigonella foenumgraecum
Kozlowski J., Nowak A., and Krajewska A., 1982. Effects of fertilizer rates and ratios on the mucilage value and diosgenin yield of fenugreek. Herba Polonica, 28(3–4):159 – 70.
Madar Z., Rachel A., Shlomith S., Joseph A., 1988. Glucose lowering effect of fenugreek in non-insulin dependent diabetics. Eur J Clin Nutr, 42: 51-54.
McCormick K, Norton R, and Eagles HA. Fenugreek has a role in south-eastern Australian farming systems. In Proceedings of “Groundbreaking stuff”, 13th. Annual Agronomy Conference, Perth, Australia. 2006, pp: 639.
Mehrafarin A., Qaderi A., Rezazadeh Sh., Naghdi Badi H., Noormohammadi Gh., and Zand E., 2010.
Bioengineering of Important Secondary Metabolites and Metabolic Pathways in Fenugreek (Trigonella foenumgraecum L.). J. of Medicinal Plants, 9(35): 1–18.
Mohamed MA., 1990. Differences in growth, seed yield and chemical constituents of fenugreek plants (Trigonella foenum-graecum L.) due to some agricultural treatments. Egyptian J. of Agronomy, 15(1–2):117– 23.
Petropoulos Gam., 1973. Agronomic, genetic and chemical studies of Trigonella foenumgraecum L. PhD. Diss. Bath University, England, 145p.
Petropoulos GA., 2002. Fenugreek, The genus Trigonella. Taylor and Francis, London and New York. p: 255.
Qureshi MI., Israr M., Abdin MZ., and Iqbal M., 2005. Responses of Artemisia annua L. to lead and salt induced oxidative stress. Environment and Experimental Botany, 53: 185-193.
Raghuram TC., Sharma RD., Sivakumar B., 1994. Effect of fenugreek seeds on intravenous glucose disposition in non-insulin dependent diabetic patients. Phytother Res, 8:83-86.
Sadeghzadeh-Ahari D., Kashi AK., Hassandokht MR., Amri A., Alizadeh Kh., 2009. Assessment of drought tolerance in Iranian fenugreek landraces. Journal of Food, Agriculture & Environment, 7(3&4): 414-419.
Sauvaire Y., Petit P., Broca C., 1998. 4-Hydroxyisoleucine: a novel amino acid potentiator of insulin secretion. Diabetes mag, 47:206-210.
Sharma RD., Raghuram TC., Rao NS., 1990. Effect of fenugreek seeds on blood glucose and serum lipids in type I diabetes. Eur J Clin Nutr, 44:301-306.
Sharma RD., Sarkar A., Hazra DK., 1996. Hypolipidaemic effect of fenugreek seeds: a chronic study in non-insulin dependent diabetic patients. Phyto Res,10: 332-334.
Tim Kr., 1998. Herbal support for diabetes management, Adva Nutr Public, 6, (8), 21-28. tissue cultures. Lloydia, 36: 96–108.
Trisonthi P., Baccou JC., and Sauvaire Y., 1980. Trial to improve production of steroidal sapogenin by fenugreek (Trigonella foenumgraecum L.) tissue grown in vitro. C.R. Seances Acad. Sci., Ser. D., 291 (3):357– 360.
Vortex health. Fenugreek. Available from:http://www.vortexhealth.net/fenugreek.html