Document Type: Original Article


1 Department of Microbiology, Lahijan Branch, Islamic Azad University Lahijan, Iran

2 Department of Clinical Sciences, Karaj branch, Islamic Azad University, Karaj, Iran


Objective: The major Fusarium toxins found in cereals and cereal-based products that can be harmful to both human and animal health are some trichothecenes, such as deoxynivalenol (DON). Methods: A recent SCOOP project, Since toxinogenic fungi are cosmopolitan, mycotoxins are environmental pollutants present in virtually all parts of the world and causing diseases (mycotoxicoses) . This cross-sectional study was carried out in Spring - Summer .T-toxin levels vary in different cities of Iran and are higher than national standard  limits(20-21μg/Kg per BW)and , therefore, according to the harvesting programs for  the wheat crop . Thus the Ardebil city with a amount of 46.3ppb and Sari, Mazandaran province center, with the least amount of T-toxin by 27.2ppb have been defined respectively. Results: Because of the non-specific clinical signs of Fusarium mycotoxicoses, data about feed quality are an important part of the case history and an inevitable part of the preventive measures is regular foodstuffs monitoring with mycological and mycotoxicological examinations. The elimination of mycotoxins from feedstuff is an open problem because the scope for mycotoxin decontamination is very limited. In countries with adequate information about mycotoxin occurrence, regular tests to control foodstuffs and detect widespread and serious toxins are currently being performed and this leads to the exclusion of products with higher than allowable limits.


Bhatnagar, D., Yu, J., Ehrlich, K.C., 2002. Toxins of filamentous fungi. ChemImmunol. 81, 167- 206. Egmond, H.P., Jonker, M., 2003. Worldwide regulations for mycotoxins in food and feed in Food and Agriculture Organization of the United Nations. Fin, K., Gremmels, J., 1999. Mycotoxins: their implications for human and animal health. Vet Q. 21 (4), 115-20. Goryacheva, I.Y., de Saeger, S., Eremin S.A., van Peteghem,. C., 2007. Immunochemical methods for rapid mycotoxin detection: Evolution from single to multiple analyte screening a review. Food Additives and Contaminants. 24, 1169-1183. Ghiasian, S.A., Maghsood, A.H., Yazdanpanah, H., Shephard, G.S., Van Der Westhuizen, L., Vismer, H.F., 2006. Incidence of Fusariumverticillioides and levels of fumonisins in corn from main production areas in Iran. J. Agric. Food. Chem. 54 (16), 6118-22.

Hussein, H.M., Franich, R.A., Baxter, M., Andrew, IG., 1989. Naturally occurring Fusarium toxins in New Zealand maize. Food. Addit. Contam. 6 (1), 49-57. Krska, R., Welzig, E., Berthiller, F., Molinelli, A., Mizaikoff, B., 2005. Advances in the analysis of mycotoxins and its quality assurance. Food. Additives. Contaminants. 22, 345-353. Lepschy, V., Gleissenthal, J., Dietrich, R., Martlbauer, E., Schuster, M., Suss, A., Terplan, G., 1989. A survey on the occurrence of Fusarium mycotoxins in Bavarian cereals from the harvest Z Lebensm Unters Forsch. 188 (6), 521-6. Maragos, C.M., 2004. Emerging technologies for mycotoxin detection. J. Toxicology. 23, 317-344. Pascale, M., Visconti, A., 2007. Overview of detection methods for mycotoxins, in: J. FLeslie, R. Bandyopadhyay and A. Visconti (eds.), Mycotoxins: detection methods, management, public health and agricultural trade. CABI Publishing, Wallingford, U.K., Chapter. 15, 173-185. Riazipour, M., ImaniFooladi. A.A., Bagherpour, G., 2012. Survey of T-2 Toxin Present in Cereals Destined for Human Consumption. Jundishapur J Microbiol. 5 (3),497-501. Reddy, K.R.N., Salleh, B. Saad, B. Abbas, H.K. Abel, C.A., Shier, W.T., 2010. An overview of mycotoxin contamination in foods and its implications for human health. Toxin Reviews. 29 (1), 3-26. Shephard ,G.S., Marasas, W.F., Leggott, N.L., Yazdanpanah, H., Rahimian, H., Safavi, N., 2000. Natural occurrence of fumonisins in corn from Iran. J. Agric. Food. Chem. 48 (5), 1860-4. Steyn, P.S., 1998. The biosynthesis of mycotoxins. Revuede medicine Veterinaire. 149, 469–478. Tanaka, K., Sago, Y., Zheng, Y., Nakagawa, H., Kushiro, M., 2007. Mycotoxins in rice. Int. J. Food. Microbiol. 119 (1-2), 59-66. Visconti, A., 2001. Analysis Of T-2 and HT-2 toxins in cereal grains by Immuno affinity clean-up and liquid chromatography with fluorescence detection. J. chromatography. 1075, 151-158. Vrabcheva, T., Gessler, R., Usleber, E., Martlbauer, E., 1996. First survey on the natural occurrence of Fusarium mycotoxins in Bulgawheat. Mycopathologia. 136 (1), 47-52. Yazdanpanah, H., Daraei, B., Saifi, Z., Rasekh, H.R., Shafaati, A., Mansour Khani,M.J.K., 1998. Natural occurrence of Fusarium mycotoxins in a corn-based product from the Iranian market. Toxicology Letters. 95(1001), 155 Zheng, M.Z., Richard, J.L., Binder, J., 2006. A review of rapid methods for the analysis of mycotoxins. Mycopathologia. 161, 261-27.