TY - JOUR ID - 6585 TI - Synthesis,Characterization, Biological Evaluation and anti corrosion activity of some new bis-piperidone Derivatives JO - International Journal of Advanced Biological and Biomedical Research JA - IJABBR LA - en SN - 2383-2762 AU - Fahed Hamak, Kholoud AD - Department of chemistry, Collegeof Science, Damascus University, Syria Y1 - 2013 PY - 2013 VL - 1 IS - 2 SP - 186 EP - 196 KW - Piperidones-4 KW - 4 KW - 4'-Diaminodipheylsulphone KW - antibacterialactivity KW - anticorrosion KW - Polarization KW - bispiperidine DO - N2 - Aseries of piperidine derivatives was synthesis by the reaction between substituted benzaldhyde ,pentanone-3,and ammonium acetate by refluxining for 1-2 hr in ethanol and the derivatives refluxed with (4,4'-Diaminodiphenyl sulphone) yielded bispiperidine ,the structures of the synthesized compounds were confirmed by spectroscopy analysis , The reported compounds were screened for their antibacterial activities against : Staphylococcus aureus, Klebsiella,Escherichia coli,pseudomonas aeruginosa,Salmonilla typhi, Enterobacter.The synthesized piperidone-4 were tested to determine their ability to inhibit corrosion of mild steel in 1mol.L-1 H2SO4 and measured by polarization measurements . Which showed that these compounds  act as mixed-type inhibitors. The studies revealed that the nitrogen of Schiff base and sulfur atome ,piperidine moiety ,and the phenyl ring assist largely in corrosion control. UR - https://www.ijabbr.com/article_6585.html L1 - https://www.ijabbr.com/article_6585_dc05817d889cf1995b17fcf894c59309.pdf ER -