Document Type : Original Article


1 Department Infectious Disease and Tropical Medicine Research Center, Zahedan University of Medical Sciences, Zahedan, IR Iran

2 Zabol Medicinal plant Research Center, Zabol, Iran

3 Zabol University of Medical Sciences, Zabol, Iran

4 Department of Biology, Faculty of Sciences, Science and Research Branch, Islamic Azad University, Kerman, IR Iran

5 Biochemistry Department., Payame Noor University, Mashhad, I.R. of Iran



The synthesis of nanoparticles from biological processes is evolving a new era of research interests in nanotechnology. The aim of this study was to determined antibacterial activity of silver nanoparticles produced by Rosmarinus officinalis L leaf extract against some human pathogenic bacteria. The formation and characterisation of AgNPs were confirmed by UV-Vis spectroscopy, energy-dispersive spectroscopy (EDX), X-ray diraction (XRD) and transmission electron microscope (TEM). All strains were obtained from standard laboratory and the minimum inhibitory concentrations were investigated by microdulition method.The result show that, the levels of MIC was observed ranges from 1.25 to 2.5 mg/ml. The highest MIC value was observed against S.pneumoniae, Hafnia alvei, S. saprophyticus.


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