Document Type : Review Article


1 Laboratory Medicine Department, Faculty of Applied Medical Sciences, Umm Al-Qura University, Makkah, 21955, Saudi Arabia

2 Glocal School of Pharmacy, Glocal University, Mirzapur Pole, Saharanpur, Uttar Pradesh, India


Background: Coronavirus disease 2019 (COVID-19) is a pandemic caused by a novel coronavirus. On 30 January 2020, the first case of the COVID-19 was reported in India and it affects the whole world. The impact of various nutrients on the human immune system. To defend itself, the human body has numerous components. The human immune system identifies molecules that are foreign to its structure and responds to them in a useful manner. When a pathogen factor enters the human body, the immune system responds by triggering an immunological response.
Methods: Symptoms of COVID-19 may vary from a mild cold to severe respiratory problems and fatality. The symptom may appear in 2 days or as long as 14 days after making contact with the COVID-19 patient.
Results: To avoiding contact with an infected person, regular hand washing, wearing a mask may help to prevent and control the COVID-19. There is no specific therapy available for COVID-19. The best way is to prevent infection is to avoid being exposed to the COVID-19. Nutrition is one of the numerous variables that influence immune system function. There is a link between the immune system and nutrition, and malnutrition should not be seen just as a calorie and protein shortage.
Conclusions: The body's defensive system should be reinforced to boost immunity, minimize illness risks, and maintain good health. Healthy eating, regular exercise, and an immunological diet, on the other hand, will be a more cost-effective and natural choice.Due to these reasons, the main aim of nourishment is not merely to gain energy andprotein, but to enhance resistance against ailments with some specific nutriment and to turn the inflammatory responsein someone’s best interests. The nutriments which show beneficial effects on the immune system are called immune nutrients and nourishment on these nutriments is called immune diet. The main fields of application of immune diet are patients undergoing surgery, traumatized, cancer, patients who need intensive care, and patients with serious infections.

Graphical Abstract

Role of Immunity Booster Diet, Spices and Herbs, Change Lifestyle: Medical Viewpoints in COVID-19


Main Subjects

  1. Khanal P, Chawla U, Praveen S, Malik Z, Malik S, Yusuf M, Khan S A, Sharma M. (2021). Study of Naturally-derived Biomolecules as Therapeutics against SARS-CoV-2 Viral Spike Protein. Journal of Pharmaceutical Research International, 33(28A): 211-220.
  2. Czeresnia R M, Trad A T A, Britto I S W, Negrini R, Nomura M L, Pires P, Costa F d S, Nomura R M Y, Ruano R. (2020). SARS-CoV-2 and Pregnancy: A Review of the Facts. Revista Brasileira de Ginecologia e Obstetrícia, 42: 562-568.
  3. Singh P, Tripathi M K, Yasir M, Khare R, Tripathi M K, Shrivastava R. (2020). Potential inhibitors for SARS-CoV-2 and functional food components as nutritional supplement for COVID-19: a review. Plant Foods for Human Nutrition, 75: 1-9.
  4. Kavitha P K. (2020). Coronavirus Disease (Covid-19) in India-An Overview. Acta Sci. Med. Sci., 4(5): 64-70.
  5. Fazeli-Nasab B. (2021). Biological Evaluation of Coronaviruses and the Study of Molecular Docking, Linalool, and Thymol as orf1ab Protein Inhibitors and the Role of SARS-CoV-2 Virus in Bioterrorism. [Research]. journal of ilam university of medical sciences, 28(6): 77-96.
  6. Rahmattullah N, Arumingtyas E L, Widyananda M H, Ahyar A N, Tabroni I. (2021). Bioinformatics Analysis of Bioactive Compounds of Four Capsicum Species against SARS-CoV-2 Infection. Int. J. Adv. Biol. Biomed. Res., 9(4): 298-319.
  7. Hamulka J, Jeruszka-Bielak M, Górnicka M, Drywień M E, Zielinska-Pukos M A. (2021). Dietary Supplements during COVID-19 outbreak. Results of Google Trends analysis supported by PLifeCOVID-19 online studies. Nutrients, 13(1): 54. https://doi.og/10.3390/nu13010054
  8. Moreb N A, Albandary A, Jaiswal S, Jaiswal A K. (2021). Fruits and Vegetables in the Management of Underlying Conditions for COVID-19 High-Risk Groups. Foods, 10(2): 389.
  9. Peter A E, Sandeep B, Rao B G, Kalpana V L. (2021). Calming the storm: natural Immunosuppressants as adjuvants to target the cytokine storm in COVID-19. Frontiers in pharmacology, 11: 2305.
  10. Galanakis C M, Aldawoud T, Rizou M, Rowan N J, Ibrahim S A. (2020). Food ingredients and active compounds against the coronavirus disease (COVID-19) pandemic: A comprehensive review. Foods, 9(11): 1701.
  11. Alkhatib A. (2020). Antiviral functional foods and exercise lifestyle prevention of coronavirus. Nutrients, 12(9): 2633.
  12. Khanna K, Kohli S K, Kaur R, Bhardwaj A, Bhardwaj V, Ohri P, Sharma A, Ahmad A, Bhardwaj R, Ahmad P. (2021). Herbal immune-boosters: substantial warriors of pandemic Covid-19 battle. Phytomedicine, 85: 153361.
  13. Zvereva E, Vandyukova I, Vandyukov A, Katsyuba S, Khamatgalimov A, Kovalenko V. (2012). IR and Raman spectra, hydrogen bonds, and conformations of N-(2-hydroxyethyl)-4, 6-dimethyl-2-oxo-1, 2-dihydropyrimidine (drug Xymedone). Russian Chemical Bulletin, 61(6): 1199-1206.
  14. Subedi L, Tchen S, Gaire B P, Hu B, Hu K. (2021). Adjunctive nutraceutical therapies for COVID-19. International Journal of Molecular Sciences, 22(4): 1963.
  15. Sohail M I, Siddiqui A, Erum N, Kamran M. (2021). Phytomedicine and the COVID-19 pandemic Phytomedicine (pp. 693-708): Elsevier.
  16. Karabulut F. (2021). Emerging trends for Harnessing plant metabolome and microbiome for sustainable food Production. Micro Environer, 1(1): 33-53
  17. Parray J A, Ali U, Mir M Y, Shameem N. (2021). A high throughputs and consistent method for the sampling and isolation of Endophytic bacteria allied to high altitude the medicinal plant Arnebia benthamii (Wall ex. G. Don). Micro Environer, 1(1): 1-6.
  18. Li S, Cheng C-S, Zhang C, Tang

G-Y, Tan H-Y, Chen H-Y, Wang N, Lai A Y-K, Feng Y. (2021). Edible and Herbal Plants for the Prevention and Management of COVID-19. Frontiers in pharmacology, 12: 900.

  1. Ahmad S, Zahiruddin S, Parveen B, Basist P, Parveen A, Parveen R, Ahmad M. (2021). Indian medicinal plants and formulations and their potential against COVID-19–preclinical and clinical research. Frontiers in pharmacology, 11: 2470.
  2. Alagawany M, Attia Y A, Farag M R, Elnesr S S, Nagadi S A, Shafi M E, Khafaga A F, Ohran H, Alaqil A A, El-Hack A. (2021). The Strategy of Boosting the Immune System Under the COVID-19 Pandemic. Frontiers in Veterinary Science, 7: 712.
  3. Junaid K, Ejaz H, Abdalla A E, Abosalif K O, Ullah M I, Yasmeen H, Younas S, Hamam S S, Rehman A. (2020). Effective immune functions of micronutrients against SARS-CoV-2. Nutrients, 12(10): 2992.
  4. Arshad M S, Khan U, Sadiq A, Khalid W, Hussain M, Yasmeen A, Asghar Z, Rehana H. (2020). Coronavirus disease (COVID‐19) and immunity booster green foods: A mini review. Food Science & Nutrition, 8(8): 3971-3976.
  5. Patel B, Sharma S, Nair N, Majeed J, Goyal R K, Dhobi M. (2021). Therapeutic opportunities of edible antiviral plants for COVID-19. Molecular and Cellular Biochemistry: 1-20.
  6. Altun H K, Ermumcu M S K, Kurklu N S. (2021). Evaluation of dietary supplement, functional food and herbal medicine use by dietitians during the COVID-19 pandemic. Public Health Nutrition, 24(5): 861-869.
  7. Pastor N, Collado M C, Manzoni P. (2021). Phytonutrient and nutraceutical action against COVID-19: current review of characteristics and benefits. Nutrients, 13(2): 464.
  8. Naja F, Hamadeh R. (2020). Nutrition amid the COVID-19 pandemic: a multi-level framework for action. European journal of clinical nutrition, 74(8): 1117-1121.
  9. Shahraki-Mojahed L, Behzadmehr R, Beigomi Z. (2021). Antimicrobial Effects of Ethanol, Methanol and Ethyl Acetate Teucrium polium and Citrullus colocynthis extract on Pseudomonas aeruginosa. Micro Environer, 1(1): 26-32.
  10. Chellappan S. (220). COVID-19: Alerting Health Professionals. Acta Scientific Women's Health, 2(4): 15-17.
  11. Wu Z, McGoogan J M. (2020). Characteristics of and important lessons from the coronavirus disease 2019 (COVID-19) outbreak in China: summary of a report of 72 314 cases from the Chinese Center for Disease Control and Prevention. Jama, 323(13): 1239-1242.