Document Type : Original Article


Department of chemistry, Collegeof Science, Damascus University, Syria


Aseries of piperidine derivatives was synthesis by the reaction between substituted benzaldhyde ,pentanone-3,and ammonium acetate by refluxining for 1-2 hr in ethanol and the derivatives refluxed with (4,4'-Diaminodiphenyl sulphone) yielded bispiperidine ,the structures of the synthesized compounds were confirmed by spectroscopy analysis , The reported compounds were screened for their antibacterial activities against : Staphylococcus aureus, Klebsiella,Escherichia coli,pseudomonas aeruginosa,Salmonilla typhi, Enterobacter.The synthesized piperidone-4 were tested to determine their ability to inhibit corrosion of mild steel in 1mol.L-1 H2SO4 and measured by polarization measurements . Which showed that these compounds  act as mixed-type inhibitors. The studies revealed that the nitrogen of Schiff base and sulfur atome ,piperidine moiety ,and the phenyl ring assist largely in corrosion control.


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