Document Type : Original Article


Mashhad University of Medical Sciences, Mashhad, Iran


In this research, we investigated basic symptoms of syndrome in illnesses of sick buildings. We designed a questionnaire and asked from male of dormitory residence. Questions of the questionnaire were more about known symptoms of buildings (Shortness of breath, inflammation, swelling and burning eyes, runny nose, malaise and fatigue, drowsiness, headache) exacerbations time intervals in the residence (6 am-2pm; 2pm-10pm and 10pm-6am) Equipment and devices that people deal with it in at least 10% ( Personal computer, copier, printer, gas cookers) and the most symptoms of creating sick building syndrome (Lack of ventilation, proximity to street noise, high humidity, contaminated materials, pollution sources also most of places of syndromes (corridors, rooms, Toilets, kitchen, upper class, almost everywhere)


Araki A, Kawai T, Eitaki Y, Kanazawa A, Morimoto K, Nakayama K, et al. Relationshipbetween selected indoor volatile organic compounds, so-called microbial VOC, and the prevalence of mucous membrane symptoms in single family homes. Sci Total Environ 2010;408(10):2208–15. [Apr 15, Epub 2010 Feb 25. 2010].
Berglund, B., Gunnarson, G., Soames, J., (2002). Reliability and validity of a sick building syndrome questionnaire. Archives of the Centre for Sensory Research 7, 83e125.
Burge, P.S., (2004). Sick Building Syndrome. Occupational and Environmental Medicine 61, 185e190.
Bornehag CG, Blomquist G, Gyntelberg F, Jarvholm B, Malmberg P, Nordvall L, et al. Dampness in buildings and health. Nordic interdisciplinary review of the scientific evidence on associations between exposure to “dampness” in buildings and health effects (NORDDAMP). . [see comment]Indoor Air 2001;11:72–86.
Bornehag CG, Lundgren B, Weschler CJ, Sigsgaard T, Hagerhed-Engman L, Sundell J. Phthalates in indoor dust and their association with building characteristics. Environ Health Perspect 2005;113(10):1399–404. [Oct].
Brunekreef B. Damp housing and adult respiratory symptoms. Allergy 1992;47:498–502.
Elke K, BegerowJ, Oppermann H, Kramer U, Jermann E, Dunemann L. Determination of selected microbial volatile organic compounds by diffusive sampling and dual-column capillary GC-FID—a new feasible approach for the detection of an exposure to indoor mould fungi? J Environ Monit 1999;1(5):445–52. [Oct].
Engvall K, Norrby C, Norback D. Sick building syndrome in relation to building dampness in multifamily residential buildings in Stockholm. Int Arch Occup Environ Health 2001;74:270–8.
Fisk WJ, Lei-Gomez Q, Mendell MJ. Meta-analyses of the associations of respiratory health effects with dampness and mold in homes. Indoor Air 2007;17:284–96.
Husman T. Health effects of indoor-air microorganisms. [see comment]Scand J Work Environ Health 1996;22:5-13.
Kim JL, Elfman L, Mi Y, Wieslander G, Smedje G, Norback D. Indoor molds, bacteria, microbial volatile organic compounds and plasticizers in schools associations with asthma and respiratory symptoms in pupils. Indoor Air 2007;17(2):153–63. [Apr].
Mendell MJ. Non-specific symptoms in office workers: a review and summary of the epidemiological literature. Indoor Air 1993:3.
Norback D, Edling C. Environmental, occupational, and personal factors related to the prevalence of sick building syndrome in the general population. Br J Ind Med 1991;48:451-62.
Norback D, Wieslander G, Nordstrom K, Walinder R. Asthma symptoms in relation to measured building dampness in upper concrete floor construction, and 2-ethyl- 1-hexanol in indoor air. Int J Tuberc Lung Dis 2000;4(11):1016–25. Nov.
Peat JK, Dickerson J, Li J. Effects of damp and mould in the home on respiratory health: a review of the literature. Allergy 1998;53:120-8.
Raw, G.J., Whitehead, C., Robertson, A.S., et al., (1995). A questionnaire for studies of sick building syndrome. Building Research Establishment Report TCR 6/95.
Sarigiannis DA, Karakitsios SP, Gotti A, Liakos IL, Katsoyiannis A. Exposure to major volatile organic compounds and carbonyls in European indoor environments and associated health risk. Environ Int 2011;37(4):743–65. [May, Epub 2011 Feb 26].
Schleibinger H, Laussmann D, Bornehag CG, Eis D, Rueden H. Microbial volatile organic compounds in the air of moldy and mold-free indoor environments. Indoor Air 2008;18(2):113–24. [Apr].
Smedje GND, Wessen B, Edling C. Asthma among school employees in relation to the school environment. Indoor Air '96, the 7th International Conference on Indoor Air Quality and Climate, 21–26
July 1996. Nagoya, Japan. Tokyo: Institute of Public Health; 1996. p. 611–6.
Wessen B, Schoeps KO. Microbial volatile organic compounds—what substances can be found in sick buildings? Analyst 1996;121(9):1203–5. [Sep].
WHO. WHO Guidelines for Indoor Air Quality: Dampness and Mould; 2009.
Wieslander G, Norback D, Venge P. Changes of symptoms, tear film stability and eosinophilic cationic protein in nasal lavage fluid after re-exposure to a damp office building with a history of flooding. Indoor Air 2007;17(1):19–27. [Feb].