Document Type : Original Article
Authors
- Omiyale Olumakinde Charles 1
- Yussuf Mubaraq Damilare 2
- Oparah Confidence Damian 3
- Jokoh Peterkings Eriuroro 4
- Ikuni Precious Ifechukwukuni 5
- Okpara Chidiebere Cyril 6
- Olofin Oluwatoyin Olabimpe 7
- Ishiaq Abdulwasiu Dolapo 8
- Ogunleye Felix Iyanu 9
- Adeleye Hannah Oreoluwa 10
1 Department of Pharmacology, Toxicology and Therapeutics, College of Medicine, University of Lagos, Lagos, Nigeria
2 Department of Biochemistry, Faculty of Life Sciences, Lagos State University, Lagos, Nigeria
3 Department of Internal Medicine, National Hospital Abuja, Abuja, Nigeria
4 Department of Pharmacy, Faculty of Pharmacy, Delta State University, Nigeria
5 Department of Pharmaceutical Microbiology, Delta State University, Abraka, Nigeria
6 Department of Biochemistry, Faculty of Life Sciences, University of Ilorin, Nigeria
7 Department of Biochemistry, School of Life Sciences, Federal University of Technology, Akure, Nigeria
8 Department of Science Education, Faculty of Education, Ekiti State University, Ado-Ekiti Ekiti, Nigeria
9 Department of Biomedical Technology, School of Basic Medical Science, The Federal University of Technology Akure, Nigeria
10 Department of Food Science and Technology, Federal University Oye Ekiti, Nigeria
Abstract
Many seaweeds, most notably brown algae, are suitable for human consumption. These plants have various possible biological actions and significant phytochemical components. The ethylacetate and dichloromethane extracts of Sargassum flutans were examined for their phytochemical composition and in vitro antioxidant activities in our research. The antioxidant capacity was evaluated using the DPPH (2, 2-diphenyl-1-picrylhydrasyl) method and the reducing power. The DPPH radical scavenging activity of an antioxidant is a well-known indicator of its capacity to eliminate free radicals. Sargassum flutans ethylacetate extracts had demonstrated effective DPPH radical reducing capability. The extract's capacity to eliminate DPPH radicals increased with concentration. The typical antioxidant and positive control employed was ascorbic acid. Ethylacetate extracts from Sargassum flutans showed more reducing power than dichloromethane. The phenolic content was also determined using the Folin-Ciocalteau reagent to evaluate the extracts' impact on total antioxidant activity. The results show that the percentage of phenolic compounds of the Sargassum futans DCM extracts was higher than that of the ethylacetate extracts. Finally, it is also noteworthy to mention that, the DPPH scavenging, reducing power, and phenolic content in these extracts of maritime macroalgae were remarkably concentration dependent.
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