Almond red leaf blotch is the most important fungal disease that is caused by the fungus Polystigma amygdalinum. Symptoms depending on the cultivar almond trees can be seen almost all year. In this study the effect of 5 fungicides (Copper oxychloride 2000 µg/ml, Bordofix 2000 µg/ml, Mancozeb 200 µg/ml, Bordo Compound 10000 µg/ml, Triforin 300 µg/ml with rep.control) was examined in a randomized complete block design with 6 treatments in 4 replications to control disease in 2009-2010 in Khorasan-e- Razavi province. The degree of severity disease in leaves (from 0 to 9) was the character to be measured. First spraying was performed after petals falling (last week of May 2010) and two spraying next fortnightly intervals. Evaluating the effect of each compound was carried out with sampling in comparison with rep. control in the last week in September. Comparison of treatments in statistical level of 5% showed that, Triforin and Mancozeb fungicides were classified in the first group, Brodofix, Bordo compound, and Copper oxychloride in second group and control in third group.