International Journal of Advanced Biological and Biomedical Research

Current Issue

By Issue

By Author

By Subject

Author Index

Keyword Index

About Journal

Aims and Scope

Indexing and Abstracting

Publication Ethics

Publication Cycle-Process Flowchart

Article Processing Charges

Publisher Business Model

Journal’s Policies for Plagiarism, Fess and Publication

Open Access Policy

Self-Archiving Policy

Authors Benefits

Journal Metrics

Related Links

FAQ

News

Editors

Editorial Policies

Guidelines for Guest Editors

Reviewers

Peer Review Process

Peer Review Policy

Nutraceuticals for the COVID-19 Prevention and Treatment

Document Type : Review Article

Authors

1 Department of Pharmaceutical Chemistry, Shreeshakti Shaikshanik Sanstha, Divine College of Pharmacy, Satana, Nashik, Affiliated to Savitribai Phule Pune University, Pune, Maharashtra 423301, India

2 Department of Pharmaceutics, Shreeshakti Shaikshanik Sanstha, Divine College of Pharmacy, Satana, Nashik, Affiliated to Savitribai Phule Pune University, Pune, Maharashtra 423301, India

Abstract

Background: The novel severe acute respiratory syndrome-related coronavirus 2 (SARS-CoV-2) was spreading rapidly in 2020, and researchers and medical professionals were working around the clock to develop effective host-directed treatments and prevent it from causing the coronavirus illness 2019 (COVID-19) pandemic.

Methods: This was done in an effort to prevent the novel severe acute respiratory syndrome-related coronavirus 2 from causing COVID-19. In 1989, Dr. Stephen combined the terms nutrition and pharmaceutical to create the phrase "nutraceutical," which was described as a dietary component or nutrient that, in addition to its nutritional value, also has health benefits, such as those that promote health and fight disease.

Results: The nutraceuticals are helpful for both preventing and treating COVID-19; therefore, they serve a dual purpose. COVID-19 is caused by the same virus that causes SARS-CoV-2, which is a severe acute respiratory syndrome. The signs and symptoms of COVID can vary, but they frequently include fever, coughing, headaches, exhaustion, problems breathing, and a loss of taste and smell.

Conclusions: To treat and prevent the symptoms of the Corona virus, nutraceuticals like minerals, antioxidants, dietary fibers, and various vitamins are used.

Graphical Abstract

Nutraceuticals for the COVID-19 Prevention and Treatment

Keywords

Main Subjects

References
  1. Lordan R, Rando HM, Greene CS. Dietary supplements and nutraceuticals under investigation for COVID-19 prevention and treatment, Msystems; 2021, 6:10-128. [Crossref], [Google Scholar], [Publisher]
  2. Parisi GF, Carota G, Castruccio Castracani C, Spampinato M, Manti S, Papale M, Di Rosa M, Barbagallo I, Leonardi S. Nutraceuticals in the Prevention of Viral Infections, including COVID-19, among the Pediatric Population: A Review of the Literature, Int. J. Mol. Sci.; 2021, 22:2465. [Crossref], [Google Scholar], [Publisher]
  3. Yang CY, Chen YH, Liu PJ, Hu WC, Lu KC, Tsai KW. The emerging role of miRNAs in the pathogenesis of COVID-19: Protective effects of nutraceutical polyphenolic compounds against SARS-CoV-2 infection, Int. J. Med. Sci; 2022, 19:1340. [Crossref], [Google Scholar], [Publisher]
  4. Rossi RE, Chen J, Caplin ME. The Role of Diet and Supplements in the Prevention and Progression of COVID-19: Current Knowledge and Open Issues, Prev. Nutr. Food Sci.; 2022, 27:137. [Crossref], [Google Scholar], [Publisher]
  5. Singh B, Eshaghian E, Chuang J, Covasa M. Do diet and dietary supplements mitigate clinical outcomes in COVID-19?, Nutrients; 2022, 14:1909. [Crossref], [Google Scholar], [Publisher]
  6. Farooq A, Abbasi MH, Khawar MB, Sheikh N. A Recent Update on the Role of Nutraceuticals in COVID-19 Infection, AJHAS; 2022, 8:ID41-. [Crossref], [Google Scholar], [Publisher]
  7. Das G, Das T, Chowdhury N, Chatterjee D, Bagchi A, Ghosh Z. Repurposed drugs and nutraceuticals targeting envelope protein: A possible therapeutic strategy against COVID-19, Genomics; 2021, 113:1129-40. [Crossref], [Google Scholar], [Publisher]
  8. Domi E, Hoxha M, Kolovani E, Tricarico D, Zappacosta B. The importance of nutraceuticals in COVID-19: What’s the role of resveratrol?, Molecules; 2022, 27:2376. [Crossref], [Google Scholar], [Publisher]
  9. Rodriguez-Leyva D, Pierce GN. The Impact of Nutrition on the COVID-19 Pandemic and the Impact of the COVID-19 Pandemic on Nutrition, Nutrients; 2021, 13:1752. [Crossref], [Google Scholar], [Publisher]
  10. Norton JC, Politis MD, Bimali M, Vyas KS, Bircan E, Nembhard WN, Amick BC, Koturbash I. Analysis of COVID-19 Pandemic on Supplement Usage and Its Combination with Self-Medication within the State of Arkansas, J. Diet. Suppl.; 2023, 20:171-98. [Crossref], [Google Scholar], [Publisher]
  11. Liu, C., Sun, C. K., Chang, Y. C., Yang, S. Y., Liu, T., & Yang, C. C. The impact of the fear of COVID-19 on purchase behavior of dietary supplements: Integration of the theory of planned behavior and the protection motivation theory, Sustainability, 2021, 13: 12900. [Crossref], [Google Scholar], [Publisher]
  12. Lordan R. Dietary supplements and nutraceuticals market growth during the coronavirus pandemic–Implications for consumers and regulatory oversight, PharmaNutrition; 2021, 18:100282. [Crossref], [Google Scholar], [Publisher]
  13. Di Matteo G, Spano M, Grosso M, Salvo A, Ingallina C, Russo M, Ritieni A, Mannina L. Food and COVID-19: preventive/co-therapeutic strategies explored by current clinical trials and in silico studies, Foods; 2020, 9:1036. [Crossref], [Google Scholar], [Publisher]
  14. Mehrotra, N., & Jadhav, K. (2021). Nutraceuticals: Potential prospect for COVID-19 management, Ann. phytomedicine, S85-S102. [Crossref], [Google Scholar], [Publisher]
  15. Estrada-Luna D, Carreón-Torres E, González-Reyes S, Martínez-Salazar MF, Ortiz-Rodríguez MA, Ramírez-Moreno E, Arias-Rico J, Jiménez-Osorio AS. Nutraceuticals for complementary treatment of multisystem inflammatory syndrome in children: A perspective from their use in COVID-19, Life; 2022, 12:1652. [Crossref], [Google Scholar], [Publisher]
  16. DiNicolantonio JJ, McCarty M, Barroso-Aranda J. Melatonin may decrease risk for and aid treatment of COVID-19 and other RNA viral infections, Open heart; 2021, 8:e001568. [Crossref], [Google Scholar], [Publisher]
  17. Pentón-Rol G, Marín-Prida J, McCarty MF. C-Phycocyanin-derived phycocyanobilin as a potential nutraceutical approach for major neurodegenerative disorders and COVID-19-induced damage to the nervous system, Curr. Neuropharmacol.; 2021, 19:2250. [Crossref], [Google Scholar], [Publisher]
  18. Harborne JB, Williams CA. Advances in flavonoid research since 1992, Phytochemistry; 2000, 55:481-504. [Crossref], [Google Scholar], [Publisher]
  19. Canistro D, Chiavaroli A, Cicia D, Cimino F, Curro D, Dell'Agli M, Ferrante C, Giovannelli L, Leone S, Martinelli G, Milella L. The pharmacological basis of the curcumin nutraceutical uses: An update, Pharmadvances; 2021, 3:421-66. [Crossref], [Google Scholar], [Publisher]
  20. Kotha RR, Luthria DL. Curcumin: biological, pharmaceutical, nutraceutical, and analytical aspects, Molecules; 2019, 24:2930. [Crossref], [Google Scholar], [Publisher]
  21. Perna A, Hay E, Sellitto C, Del Genio E, De Falco M, Guerra G, De Luca A, De Blasiis P, Lucariello A. Antiinflammatory Activities of Curcumin and Spirulina: Focus on Their Role against COVID-19, J. Diet. Suppl.; 2023, 20:372-89. [Crossref], [Google Scholar], [Publisher]
  22. Jayawardena R, Sooriyaarachchi P, Chourdakis M, Jeewandara C, Ranasinghe P. Enhancing immunity in viral infections, with special emphasis on COVID-19: A review, Diabetes Metab. Syndr.; 2020, 14:367-82. [Crossref], [Google Scholar], [Publisher]
  23. Srivastava A, Gupta RC, Doss RB, Lall R. Trace minerals, vitamins and nutraceuticals in prevention and treatment of COVID-19, J. Diet. Suppl.; 2022, 19:395-429. [Crossref], [Google Scholar], [Publisher]
  24. Akour A. Probiotics and COVID‐19: is there any link?, Lett. Appl. Microbiol.; 2020, 71:229-34. [Crossref], [Google Scholar], [Publisher]
  25. Darenskaya M, Kolesnikova L, Kolesnikov S. The association of respiratory viruses with oxidative stress and antioxidants. Implications for the COVID-19 pandemic, Curr. Pharm. Des.; 2021, 27:1618-27. [Crossref], [Google Scholar], [Publisher]
  26. Babaei F, Nassiri‐Asl M, Hosseinzadeh H. Curcumin (a constituent of turmeric): New treatment option against COVID‐19, Food Sci. Nutr.; 2020, 8:5215-27. [Crossref], [Google Scholar], [Publisher]
  27. Gupta H, Gupta M, Bhargava S. Potential use of turmeric in COVID‐19, Clin. Exp. Dermatol.; 2020, 45:902-3. [Crossref], [Google Scholar], [Publisher]
  28. Panyod S, Ho CT, Sheen LY. Dietary therapy and herbal medicine for COVID-19 prevention: A review and perspective, J. Tradit. Complement. Med.; 2020, 10:420-7. [Crossref], [Google Scholar], [Publisher]
  29. Ang L, Lee HW, Choi JY, Zhang J, Lee MS. Herbal medicine and pattern identification for treating COVID-19: a rapid review of guidelines, Integr. Med. Res.; 2020, 9:100407. [Crossref], [Google Scholar], [Publisher]
  30. Norrie JD. Remdesivir for COVID-19: challenges of underpowered studies, Lancet; 2020, 395:1525-7. [Crossref], [Google Scholar], [Publisher]
  31. Grant WB, Lordan R. Vitamin D for COVID-19 on trial: An update on prevention and therapeutic application, Endocr. Pract.; 2021, 27:1266-8. [Crossref], [Google Scholar], [Publisher]
  32. Pawar SD, Deore SD, Bairagi NP, Deshmukh VB, Lokhande TN, Surana KR. Vitamins as Nutraceuticals for Anemia, Vitamins as Nutraceuticals: Recent Advances and Applications; 2023, 26:253-79. [Crossref], [Google Scholar], [Publisher]
  33. Pathan AS, Jain PG, Mahajan AB, Kumawat VS, Ahire ED, Surana KR, Rajora AK, Rajora MA. Beneficial Effects of Water‐Soluble Vitamins in Nutrition and Health Promotion, Vitamins as Nutraceuticals: Recent Advances and Applications; 2023, 26:235-51. [Crossref], [Google Scholar], [Publisher]
  34. Parkhe AG, Surana KR, Ahire ED, Mahajan SK, Patil DM, Sonawane DD. Impact of Vitamins on Immunity, Vitamins as Nutraceuticals: Recent Advances and Applications; 2023, 26:87-106. [Crossref], [Google Scholar], [Publisher]
  35. Gaikwad J, Jogdand S, Pathan A, Mahajan A, Darak A, Ahire ED, Surana KR. Nutraceuticals Potential of Fat‐Soluble Vitamins, Vitamins as Nutraceuticals: Recent Advances and Applications; 2023, 26:107-28. [Crossref], [Google Scholar], [Publisher]
  36. Ahire ED, Sonawane VN, Surana KR, Jadhav KR, Sonawane DD, Shah AA. Convalescent plasma therapy: A promising approach in the treatment of Covid-19, Int. J. Pharm. Sci. Res.; 2020, 11:4078-86. Google Scholar], [Publisher]
  37. Lokhande TN, Varma KS, Gharate SM, Mahajan SK, Surana KR. Vitamins as Nutraceuticals for Pregnancy, Vitamins as Nutraceuticals: Recent Advances and Applications; 2023, 26:185-204. [Crossref], [Google Scholar], [Publisher]
  38. Surana KR, Ahire ED, Patil SJ, Mahajan SK, Patil DM, Sonawane DD. Introduction to Nutraceutical Vitamins, Vitamins as Nutraceuticals: Recent Advances and Applications; 2023, 26:1-34. [Crossref], [Google Scholar], [Publisher]
  39. Pathan A, Mahajan MM, Jain PG, Zambad SP, Bhandari GS, Darak AD, Ahire ED, Rajora AK, Surana KR. Nutraceutical Properties of Seaweed Vitamins, Vitamins as Nutraceuticals: Recent Advances and Applications; 2023, 26:167-84. [Crossref], [Google Scholar], [Publisher]
  40. Pawar SD, Deore SD, Bairagi NP, Deshmukh VB, Lokhande TN, Surana KR. Vitamins as Nutraceuticals for Anemia, Vitamins as Nutraceuticals: Recent Advances and Applications; 2023, 26:253-79. [Crossref], [Google Scholar], [Publisher]

 

International Journal of Advanced Biological and Biomedical Research
Volume 11, Issue 4
October 2023
Pages 247-260
Files
History
  • Receive Date: 03 September 2023
  • Revise Date: 06 October 2023
  • Accept Date: 21 October 2023
Share
How to cite
Statistics