Document Type : Review Article
1 Department of Animal Science, Shahid Bahonar University, Kerman, Iran
2 Young Researchers and Elite Club, Kerman Branch, Islamic Azad University, Kerman, Iran
For centuries, Aloe Vera has been used by many different cultures. The ancient Greeks, the Romans, the Babylonians, Indians and the Chinese have all used Aloe Vera as a medicinal plant. One of the common experimental cancer models is sarcoma-180. When Aloe was administered to mice bearing S-180 tumors, the tumor growth was inhibited. Aloe vera is a dietary supplement and not a regulated drug. There is no guarantee of strength, purity, or safety of these products. Aloe vera is approved by the Food and Drug Administration as a food additive for flavor.
Al Awadi FM: Studies on the activity of individual plants of anantidiabetic plant mixture. Acta Diabetol Lab. 24:1:37-41, Jan-Mar. 1987.
American Osteopathic Association 62:731-735, 1963.
American Podiatric Medical Assn. 79:8:395-397, Aug. 1989.
Bacteriostatic property of Aloe vera.: Journal of Pharmaceutical Science 53:1287, 1964.
Bruce WGG: Investigations of the antibacterial activity in the Aloe. South African Medical Journal 41:984, 1967.
Cole HN; Chen KK: Aloe vera in Oriental dermatology. Archives of Dermatology and Syphilology 47:250, 1943.
Dixit VP: Effects of Aloe barbadensis and clofibrate on serum lipids in tritoninduced hyperlipidemia in presbyter entellus rnonkeys. Indian Journal of Medical Research 78:417-421, 1983.
El Zawahry M; Hegazy MR; Helal M: Use of Aloe in treating leg ulcers and dermatoses. International Journal of Dermatology 12:68-73, 1973.
Faculty of Baylor University in partial fulfillment of the requirements for the Degree of Master of Sciences).
Fan YS, et. al.: Protective effect of extracts from Aloe vera L. var. chinensis on experimental hepatic lesions and a primary clinical study on the injection of in-patients with hepatitis. Chung Kuo Chung Yao Tsa Chih 14:12:746-748, Dec. 1989.
gel on tissue culture cells. Oral Surgery, Oral Medicine & Oral Pathology 27:122-128, 1969.
Ghannam M; Kingston M: Antidiabetic activity of Aloes preliminary clinical and experimental observations. Horm. Res. 24:4:288-294, 1986.
Gjerstad G; Riner TD: Current status of Aloe as a cure all. American Journal of Pharmacy 140:58-64, 1968.
Gribel NV; Pashinski VG: Antimetastatic’ properties of Aloe juice. Vopr Onkol 32:12:38-40, 1986 (Russia).
High energy electron injury. Annals of Surgery 162:3:435, 1962.
Kameyama S; Shinho M: Wound healing compositions from Aloe arborescens extracts. Japanese patent 79,151,113. Chemical Abstracts 93:10375y, 1980.
Kandel A; Gbran W: Protection of gastric mucosa by Aloe vera. Journal of Drug Research 11:191-196, 1979 (Egypt).
lesions (use of Aloe vera). Cancer Journal for Clinicians 14:14-15, 1963.
Loveman AB: Leaf of Aloe vera in treatment of Roentgen ray ulcers. Archives of Dermatology and Syphilology 36:838-843, 1937.
McAnalley BW, PhD., et. al.: Demonstration of in-vitro antiviral action of Acemannan against multiple viruses including the HIV virus. Presented at IV International Conference on AIDS (Stockholm, Sweden, June 1988).
Meadows TP: Aloe as a humectant in new skin preparations. Cosmetics and Toiletries 95:51-56, 1980.
Winters WD; Benavides R; Clouse WJ: Effects of Aloe extracts on human normal and tumor cells in vitro. Economic Botany 35:89-95, 1981.
Nikolaeva VG: Plants used by people of the USSR for treatment of infected wounds. Farmatsiya 28:46 49, 1979 (Moscow).
Northway RB: Experimental use of Aloe vera extract in clinical practice. Veterinary Medicine/Small Animal Clinician 70:89, 1975.
Payne JM (1970): Tissue responses to Aloe vera gel following periodontal surgery. (Thesis submitted to Perry SY, M.D., et. al.: Decreased mortality of normal murine sarcoma in mice treated with the
immunomodulator, Acernannan. Molecular Biotherapeutics 3:79-87, June 1991. Podiatric Medical Assn. 79:11:559-562, Nov. 1989.
presbyter entellus rnonkeys. Indian Journal of Medical Research 78:417-421, 1983.
Pulse TL; Uhlig, Elizabeth: A significant improvement in a clinical pilot study utilizing nutritional supplements, essential fatty acids and stabilized Aloe vera juice in 29 HIV seropositive, ARC and AIDS patients. Journal of Advancement in Medicine 3:4, Winter 1990.
Rovatti B; Brennan RJ: Experimental thermal burns - a comparative study of the immediate and elayed histopathological changes in the skin in untreated and treated thermal burns. Industrial Medicine and
Surgery 28:8:364-368, Aug., 1959.
Sato Y: Protection effects of Aloe arborescens on skin injury by X-irradiation. Yakmgakn Zasshi 110:11:876-884, Nov. 1990 (Japan).
Sheets, Mark, D.V.M., et al.: Studies on the effect of Acemannan on retrovirus infections: clinical stabilization of feline leukemia virus-infected cats. Molecular Biotherapy 3:41-45, Mar. 1991.
Soeda M: Studies on the anti-tumor activity of Cape Aloe. Journal of the Medical Society of Toho University 16:365-369, 1969 (Japan).
Soeda M; Fujiwara M; Otomo M: Studies on the effect of Cape Aloe for irradiation leukopenia. Nippon Acta Radiologica 24:1109-1112, 1964.
Soeda M; Otomo M; Ome M; Kawashima K: Studies on antibacterial and antifungal activity of Cape Aloe. Nippon Saikingaku Zasshi 21:609-614, 1966.
Sotnikovg EP: Therapeutic use of Aloe in experimental stomach ulcers (Lechebnoe primenie Aloe prieksperimental). ’Nych Igzvakh Zhelukka Vrach Deb 6:71-74, June 1984 (Russia).
Wright CS: Aloe vera in the treatment of Roentgen ulcers and telangiectasis. Journal of the American Medical Association l06:1363-1364, 1936.
Yahgi A, et. al.: Antibradykinin active material in Aloe saponaria. Journal of Pharmaceutical Sciences 71:1172-1174, 1982.