International Journal of Advanced Biological and Biomedical Research

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37
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Functional Assessment of CODM Gene in Different Cultivar of Papaveraceous Species Via In Silico Analysis

Document Type : Original Article

Authors

Seyedeh Habibeh Hosseini 1
Hossein Azarnivand 1
Mohammad Reza Naghavi 2

1 Department of Reclamation of Arid and Mountainous Region, Natural Resources Factually, the University of Tehran, Karaj, Iran

2 Agronomy and Plant Breeding Department (APBD), College of Agriculture and Natural Resources, the University of Tehran, Karaj, Iran

Abstract
Medicinal use of the opium poppy (Papaver somniferum L) has ancient history, but the isolation of morphine was not described until the early nineteenth century. Morphine is the most important alkaloid of opium poppy in the last 50 years. In the morphine pathway has been reported to generate morphine in this species, CODM has a crucial role as the gene coding the enzyme responsible for demethylation of codeine to morphine. In this study we extract of CODM gene sequence from Papaver fogax and Papaver oriental. The sequence of this gene via in silico technique converted to the protein sequence.  After this step we use the bioinformatics tools for analysis of these sequences.

Keywords

CODM gene
Papaveraceous species
Homology modeling
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International Journal of Advanced Biological and Biomedical Research
Volume 2, Issue 5 - Serial Number 5
May and June 2014
Pages 1606-1612

  • Receive Date 31 July 2014

Article View 19,953
PDF Download 7,572

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